Metazine CR 35 Tablet is an anti-anginal medicine used for treating heart-related chest pain (angina). It prevents new attacks of angina but does not stop an acute attack once it has started. It can be used alone or in combination with some other medicines.

Metazine CR 35 Tablet is a medicine used for treating heart-related chest pain (angina) caused due to narrowing of blood vessels of the heart. It effectively prevents new attacks of angina but does not stop an acute attack once it has started. This medicine should be used along with lifestyle changes like healthy diet, regular exercise, and smoking cessation for best results. It is used as an add-on therapy for patients who are not relieved by or are intolerant to the initial medicines. It should not be stopped abruptly. Headache, vomiting, and dizziness may be seen as side effects.

Uses of Metazine Tablet MR

Treatment of Angina (heart-related chest pain)

Benefits of Metazine Tablet MR

In Treatment of Angina (heart-related chest pain)

Angina is chest pain or discomfort that happens when there is not enough oxygen-rich blood going to part of your heart. This can occur when the blood vessels of the heart become narrow. By preserving energy metabolism in cells exposed to reduced oxygen supply, Metazine CR 35 Tablet prevents a decrease in intracellular energy levels, thereby ensuring the proper functioning of heart muscle cells. Metazine CR 35 Tablet can also help increase your ability to exercise and lead your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Research shows that the frequency of angina attacks reduces significantly after 6 months of treatment with Metazine CR 35 Tablet.

Side effects of Metazine Tablet MR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metazine

Dizziness
Headache
Nausea
Vomiting
Weakness
Rash
Abdominal pain
Indigestion
Itching
Diarrhea
Hives

How to use Metazine Tablet MR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metazine CR 35 Tablet is to be taken with food.

How Metazine Tablet MR works

Metazine CR 35 Tablet is an anti-anginal medication. It decreases the oxygen requirement of the heart by shifting its metabolism from fats to glucose. As a result, the heart works more efficiently.

Safety advice

Alcohol

UNSAFE

Metazine CR 35 Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Metazine CR 35 Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Metazine CR 35 Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Metazine CR 35 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Metazine CR 35 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metazine CR 35 Tablet may be needed. Please consult your doctor.
Use of Metazine CR 35 Tablet is not recommended in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Metazine CR 35 Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Metazine CR 35 Tablet

₹12.6/Tablet MR

Flavedon MR Tablet

Serdia Pharmaceuticals India Pvt Ltd

₹13.09/tablet mr

13% costlier

Carvidon -MR Tablet

Micro Labs Ltd

₹15.5/tablet mr

34% costlier

Trivedon MR Tablet

Cipla Ltd

₹17.1/tablet mr

47% costlier

FLAVMOX 35MG TABLET MR

Maxlive Pharmaceuticals Pvt Ltd

₹9.2/tablet mr

21% cheaper

Trimezen 35mg Tablet MR

Elder Pharmaceuticals Ltd

₹8/tablet mr

31% cheaper

View all substitutes

Quick tips

Metazine CR 35 Tablet prevents new attacks of angina but does not stop an acute attack.
Does not affect heart rate, blood pressure at rest or during exercise.
Improves HbA1c and blood sugar levels in diabetes patients.
Avoid driving or using machinery if you feel dizzy after taking Metazine CR 35 Tablet.

Fact Box

Chemical Class

Phenylmethylamines

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Fatty acid modulator & Sodium channel blocker

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Interventional Cardiology

Related to chest pain angina commonly

Chest pain headache vetrigo Angina pain

Dr. Nabajit Talukdar

Interventional Cardiology

Get echo n ECG done

FAQs

Is Metazine CR 35 Tablet a beta blocker?

No, Metazine CR 35 Tablet is not a beta blocker. It is an anti-anginal medicine which is used in combination with other medicines to treat angina pectoris (chest pain caused by coronary disease). It protects the heart cells from getting affected by the reduced oxygen supply during an episode of angina.

Who should not take Metazine CR 35 Tablet?

You should not take Metazine CR 35 Tablet if you are allergic to it or have severe kidney problems. Patients with Parkinson’s disease should also avoid taking Metazine CR 35 Tablet. Parkinson’s disease is a disease of the brain which affects movement and causes trembling, rigid posture, slow movements and a shuffling, unbalanced walk.

Can Metazine CR 35 Tablet be used in elderly patients?

Metazine CR 35 Tablet should be used with caution in patients aged more than 75 years of age. Usually, a lower dose is prescribed in elderly patients to reduce the chances of adverse effects. It is important to continuously monitor such patients.

Does taking Metazine CR 35 Tablet increases the risk of falling down frequently?

Though it is rare, falls may occur with use of Metazine CR 35 Tablet. This may be due to instability while walking or fall in blood pressure while standing up. The risk may be higher in elderly patients. Therefore, they need to be more careful and should be monitored.

Does Metazine CR 35 Tablet cause drowsiness?

Yes, Metazine CR 35 Tablet may make you feel dizzy and drowsy. Therefore, you should avoid driving or using heavy machinery in case it causes these side effects.

How should Metazine CR 35 Tablet be taken?

You should take Metazine CR 35 Tablet exactly as prescribed by your doctor. It is meant for oral use. So, take the tablets with sufficient amount of liquid, e.g. a glass of water. You can take this medicine with or without food.

What are the possible side effects of Metazine CR 35 Tablet?

The common side effects of Metazine CR 35 Tablet include dizziness, headache, abdominal pain, diarrhea, indigestion, and hives, rash and itching. Its use may also make you feel sick and weak. The rare side effects may include fast or irregular heartbeats (also called palpitations), fall in blood pressure on standing which can further cause dizziness, lightheadedness or fainting, fall, and flushing.

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References

Trimetazidine dihydrochloride. Suresnes Cedex, France: Les Laboratoires Servier; 2001 [revised 27 Mar. 2007]. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
CiplaMed. Trimetazidine dihydrochloride [Prescribing Information]. [Accessed 07 Aug. 2023]. (online) Available from:
Trimetazidine dihydrochloride [Package leaflet: Information for the user]. Gidy, France: Les Laboratoires Servier Industrie; 2021. [Accessed 07 Aug. 2023]. (online) Available from:
Ciapponi A, Pizarro R, Harrison J. WITHDRAWN: Trimetazidine for stable angina. Cochrane Database Syst Rev. 2017 Mar 20;3(3):CD003614. [Accessed 07 Aug. 2023]. (online) Available from:

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