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05 Dec 2023 | 06:14 PM (IST)

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Product introduction

Zemisam 400mg Tablet is a medicine used for the treatment of liver disease associated with reduced bile formation (intrahepatic cholestasis). It protects the liver cells from toxins and helps the liver to perform its normal functions.

Zemisam 400mg Tablet may be taken with or without food. The dose will depend on the severity of your condition and your body weight. It is best swallowed whole, but you may need to break them to get the correct dose. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.

Use of this medicine may cause some common side effects such as headache, dizziness, vomiting, upset stomach, diarrhea, constipation, increased sweating, and insomnia. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea and constipation.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.

Uses of Zemisam Tablet

Benefits of Zemisam Tablet

In Treatment of Liver disease

Zemisam 400mg Tablet protects the liver from damage against harmful chemicals, thereby improving overall health of the liver. This helps the liver to perform its normal functions. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.

Side effects of Zemisam Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zemisam

  • Headache
  • Dizziness
  • Vomiting
  • Upset stomach
  • Diarrhea
  • Constipation
  • Increased sweating
  • Insomnia (difficulty in sleeping)

How to use Zemisam Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zemisam 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zemisam Tablet works

Zemisam 400mg Tablet contains S-Adenosyl L-Methoinine Disulfate Tosylate, also known as SAMe, a nutritional supplement, that can restore Glutathione concentrations in the liver and also improves liver damage. SAMe is also involved in many biochemical reactions in the human body that regulate the growth, death and differentiation of hepatocytes (liver cells). Because liver function is compromised in people suffering from liver disease, supplementation with Zemisam 400mg Tablet is beneficial.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Zemisam 400mg Tablet.
Pregnancy
SAFE IF PRESCRIBED
Zemisam 400mg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Zemisam 400mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Zemisam 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Zemisam 400mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Zemisam 400mg Tablet is safe to use in patients with liver disease. No dose adjustment of Zemisam 400mg Tablet is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zemisam 400mg Tablet
β‚Ή53.9/Tablet
Livsam 400mg Tablet
Skyglow Pharmaceuticals Private Limited
β‚Ή49/tablet
9% cheaper
Samydep 400mg Tablet
Amytree Pharmaceuticals
β‚Ή65/tablet
21% costlier
SI Max 400mg Tablet
Trans Life Sciences
β‚Ή5.8/tablet
89% cheaper
Admyl S 400mg Tablet
Drukst Biotech Private Limited
β‚Ή55/tablet
2% costlier
Lesamy 400mg Tablet
Leeford Healthcare Ltd
β‚Ή62/tablet
15% costlier

Quick tips

  • Zemisam 400mg Tablet is prescribed for the treatment of liver disease.
  • Seek immediate medical attention if you have difficulty breathing after taking the drug.
  • Zemisam 400mg Tablet may interfere with surgery. Its use should be discontinued at least two weeks prior to surgery.
  • Avoid smoking and drinking as it further degrades liver functioning.
  • You will be regularly monitored for blood creatinine and blood/urine urea levels while on treatment with Zemisam 400mg Tablet.

Fact Box

Chemical Class
5'-deoxy-5'-thionucleosides
Habit Forming
No

Patient concerns

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Guo T, Chang L, Xiao Y, et al. S-adenosyl-L-methionine for the treatment of chronic liver disease: A systematic review and meta-analysis. PLoS One. 2015;10(3):e0122124. [Accessed 02 Jul. 2021] (online) Available from:External Link
  2. Noureddin M, Sander-Struckmeier S, Mato JM. Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review. World J Hepatol. 2020;12(2):46-63. [Accessed 02 Jul. 2021] (online) Available from:External Link

Marketer details

Name: Stanley Pharmaceuticals
Address: 18, KHAZOOR BLDG., BHAGIRATH PLACE, DELHI
Country of origin: India

MRP
β‚Ή539
Inclusive of all taxes
10.0 tablets in 1 strip
SOLD OUT
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