Pramipex 1.25mg Tablet ER is used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements.

Pramipex 1.25mg Tablet ER is used to treat Parkinson's disease (a disorder of the nervous system that causes difficulties with movement and balance) and also has multiple other actions

Uses of Pramipex Tablet ER

Benefits of Pramipex Tablet ER

In Parkinson's disease

Pramipex 1.25mg Tablet ER is effective in relieving symptoms of Parkinson's disease such as tremors, muscle stiffness, and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in the coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

In Restless leg syndrome

Restless leg syndrome is a condition that causes an uncontrollable urge to move your legs, usually because of an uncomfortable sensation. It typically happens in the evening or nighttime hours when you're sitting or lying down. Moving or walking, that is change in posture, will control the unpleasant feeling temporarily. Pramipex 1.25mg Tablet ER helps to relieve this uncomfortable urge and calms these sensations. Take it as advised by the doctor to get the maximum relief.

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Side effects of Pramipex Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pramipex

Dizziness
Sleepiness
Nausea
Dryness in mouth
Fatigue
Hallucination
Constipation
Peripheral edema
Muscle spasm

How to use Pramipex Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pramipex 1.25mg Tablet ER is to be taken with food.

How Pramipex Tablet ER works

Pramipex 1.25mg Tablet ER works by mimicking the action of dopamine, a chemical messenger that is needed to control movement in the brain.

Safety advice

Alcohol

UNSAFE

Pramipex 1.25mg Tablet ER may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Pramipex 1.25mg Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Pramipex 1.25mg Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pramipex 1.25mg Tablet ER suppresses serum prolactin and may interfere with breastfeeding.

Driving

UNSAFE

Pramipex 1.25mg Tablet ER may cause side effects which could affect your ability to drive.
Pramipex 1.25mg Tablet ER can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.

Kidney

CAUTION

Pramipex 1.25mg Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Pramipex 1.25mg Tablet ER may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Pramipex 1.25mg Tablet ER is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pramipex 1.25mg Tablet ER may not be needed in these patients. Please consult your doctor.

What if you forget to take Pramipex Tablet ER?

If you miss a dose of Pramipex 1.25mg Tablet ER, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

You have been prescribed Pramipex 1.25mg Tablet ER to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
It can be taken with or without food. Taking it with food may reduce nausea.
For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
When you first start taking Pramipex 1.25mg Tablet ER, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Talk to your doctor in case you develop hallucinations or other changes in your behavior.
Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Benzothiazole Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Dopamine agonists

Patient concerns

I feel tingling in my legs,whenever i close my eyes.rls is the name of disease.i want treatment, as i am taking pramipex 1mg twice a day Plz guide me properly

Dr. Jyoti Kapoor Madan

Psychiatry

Restless Leg Syndrome or RLS is a neurological disorder. Pramipexol is a treatment modality. Your neurologist can advise you about other options if it doesn't work for you.

Post L5 S1 surgery my right leg numbness still persist. As per advise taking lyrica 75 mg n evion LC daily. But no use pls advise

Dr. Vikas Sharma

Neurology

try tab pramipex 0.25 mg HS

User feedback

Patients taking Pramipex 1.25mg Tablet ER

Once A Day

50%

Thrice A Day

30%

Twice A Day

20%

FAQs

Does Pramipex 1.25mg Tablet ER cause weight gain?

A common side effect of Pramipex 1.25mg Tablet ER is decrease in body weight which may be due to decrease in appetite. Uncommonly, it can also cause increase in weight. However, if you have concerns regarding your weight talk to your doctor or a nutritionist.

Does Pramipex 1.25mg Tablet ER make you sleepy?

Yes, Pramipex 1.25mg Tablet ER may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery and inform your doctor.

How does Pramipex 1.25mg Tablet ER work for restless legs?

Restless leg syndrome (RLS) is a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down. Pramipex 1.25mg Tablet ER belongs to dopamine (neurotransmitter) agonist class of medicines. It acts by stimulating the dopamine receptors which is needed in the brain to control movement. Hence, it is used to improve RLS.

Is Pramipex 1.25mg Tablet ER a muscle relaxant?

No, Pramipex 1.25mg Tablet ER is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.

Can I stop taking Pramipex 1.25mg Tablet ER if my symptoms of Parkinson’s disease have improved?

You should not stop Pramipex 1.25mg Tablet ER without talking to your doctor. Sudden discontinuation of Pramipex 1.25mg Tablet ER may cause neuroleptic malignant syndrome. The symptoms of malignant syndrome include loss of muscle movement, rigid muscles, fever, unstable blood pressure, increased heart rate, confusion, and depressed level of consciousness.

How should Pramipex 1.25mg Tablet ER be taken?

You should take Pramipex 1.25mg Tablet ER as directed by your doctor. The doctor will decide your dose depending on the condition you are being treated for. Preferably it should be taken 2-3 hours before bedtime. Swallow the tablets whole with water. It can be taken with or without food, but taking it with food may help reduce the chances of nausea.

What are the serious side effects of Pramipex 1.25mg Tablet ER?

The serious side effects of Pramipex 1.25mg Tablet ER include hallucinations (seeing things or hearing voices that do not exist), confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, abnormal body movements, and motions that you cannot control. It may also cause changes in the way you sit or stand that you cannot control, such as your neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand or walk. Additionally, it may cause dark, red or cola-colored urine, muscle tenderness, muscle stiffness or aching and muscle weakness. Call your doctor immediately if you experience any of these.

What are impulse control disorders caused by Pramipex 1.25mg Tablet ER?

Pramipex 1.25mg Tablet ER may cause impulse control disorders in which you may have cravings or urge to behave in an unusual manner, which normally you would not do. Pramipex 1.25mg Tablet ER may also make it hard for you to resist the impulse to carry certain activities which can harm you or others, like addictive gambling, excessive eating or spending money. Along with that, it may cause an abnormally high sex drive or preoccupation with an increase in sexual thoughts or feelings.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 475-76.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1140-41.
Pramipexole dihydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim International GmbH; 2010. [Accessed 22 Jan. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
Pramipexole. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 7 Feb. 2018]. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Aug. 2023] (online) Available from:
Pramipexole dihydrochloride [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021. [Accessed 05 Aug. 2023] (online) Available from:

Marketer details

Name: Sun Pharmaceutical Industries Ltd

Address: 90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001

Country of origin: India
Expires on or after: March, 2025

A licensed vendor partner from your nearest location will deliver Pramipex 1.25mg Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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