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Pregabalin + Duloxetine
Information about Pregabalin + Duloxetine
Pregabalin + Duloxetine Uses
Pregabalin+Duloxetine is used in the treatment of neuropathic pain.
How Pregabalin + Duloxetine works
Pregabalin + Duloxetine is a combination of two medicines: Pregabalin and duloxetine. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).
Common side effects of Pregabalin + Duloxetine
Nausea1a, Constipation, Insomnia (difficulty in sleeping), Sleepiness, Headache, Dizziness, Tiredness, Ejaculation disorder, Erectile dysfunction, Uncoordinated body movements
Available Medicine for Pregabalin + Duloxetine
Expert advice for Pregabalin + Duloxetine
- Pregabalin + Duloxetine is used for treating nerve pain caused by diabetes, shingles, fibromyalgia, and spinal cord injuries.
- You may have to wait for 2 to 4 weeks before it starts working.
- It may cause dizziness during the first few weeks. Don't drive or do anything requiring concentration until you know how Pregabalin + Duloxetine affects you.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
- Monitor your blood pressure regularly, especially during the first month of treatment.
- It may cause a sensation of restlessness or an inability to sit or stand still, especially when you first start taking it. Inform your doctor if this happens to you.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor.