Tolvaptan

Information about Tolvaptan

Tolvaptan Uses

Tolvaptan is used in the treatment of syndrome of inappropriate antidiuretic hormone secretion (SIADH) and low levels of sodium in the blood. It treats low levels of sodium in the blood, which can result from conditions such as heart failure, cirrhosis and syndrome of inappropriate antidiuretic hormone (SIADH).

How Tolvaptan works

Tolvaptan is a vasopressin antagonist. It works by blocking the effect of the hormone vasopressin in the body. This increases urine production, reduces the amount of water in the blood and raises the blood sodium level.

Common side effects of Tolvaptan

Dryness in mouth, Increased thirst, Dizziness, Nausea, Fatigue, Polyuria, Diarrhea
CONTENT DETAILS
Written By
Dr. Balshine Singh Kanwar
MD, MBBS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Written By
Dr. Betina Chandolia
MDS, BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
08 Nov 2024 | 06:37 AM (UTC)

We provide you with authentic, trustworthy and revelant information

Want to know more

Available Medicine for Tolvaptan

NatriseSun Pharmaceutical Industries Ltd
₹587 to ₹11002 variant(s)
ResodimLupin Ltd
₹803 to ₹12732 variant(s)
Hyponat-OZydus Cadila
₹7471 variant(s)
TolvatMSN Laboratories
₹616 to ₹11812 variant(s)
TolvascaGlenmark Pharmaceuticals Ltd
₹824 to ₹11502 variant(s)
TvaptanCentaur Pharmaceuticals Pvt Ltd
₹602 to ₹11013 variant(s)
TolsamaMSN Laboratories
₹685 to ₹8252 variant(s)
TolvamacMacleods Pharmaceuticals Pvt Ltd
₹634 to ₹7562 variant(s)
ShiokemAlkem Laboratories Ltd
₹440 to ₹8002 variant(s)
TolvagenLG Lifesciences
₹396 to ₹7562 variant(s)

Expert advice for Tolvaptan

  • Tolvaptan treats low sodium levels in the blood.
  • It also improves urine flow without causing the body to lose too much sodium as you urinate.
  • Take it at the same time everyday. Take it according to the dose and duration prescribed by your doctor.
  • To avoid dehydration, it is best to drink something as soon as you feel thirsty, but avoid alcoholic drinks.
  • Do not take Tolvaptan if you are unable to urinate, if you are unable to tell when you are thirsty, or if you are severely dehydrated.
  • You will need to be in a hospital under observation any time you start or restart treatment with Tolvaptan.
  • Inform your doctor if you notice problems with speech or muscle control, trouble swallowing, trouble moving your arms and legs, or mood changes.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

Frequently asked questions for Tolvaptan

Tolvaptan

Q. What is the most important information I need to be aware of while taking Tolvaptan?

Tolvaptan may cause the level of sodium in your blood to increase too quickly. This quick increase in sodium levels [osmotic demyelination syndrome (ODS)] may cause serious nerve damage, which can further cause coma and even death. The symptoms of ODS could be trouble in speaking, trouble in swallowing or a feeling of food or liquid getting stuck while swallowing, drowsiness, confusion, mood changes, fits, trouble controlling body movement (involuntary movement) and weakness in muscles of the arms and legs.

Q. For how long do I need to take Tolvaptan?

Tolvaptan is used for correction of sodium levels in blood. Though the dose and duration are prescribed by the doctor, Tolvaptan should not be taken for more than 30 days. Once the sodium levels return to normal, it can be stopped after talking to the doctor.

Q. Does Tolvaptan affect the sugar levels in blood?

Yes, Tolvaptan may increase the blood sugar levels. Therefore, patients with diabetes mellitus need to be extra careful while taking Tolvaptan and should keep a check on blood sugar levels regularly.

Q. Who should not take Tolvaptan?

You should not take Tolvaptan if you have low sodium levels, cannot replace fluids by drinking or if you cannot tell when you are thirsty, dizzy or feeling faint or if your kidneys are not working properly because of excessive loss of fluids. You should also avoid Tolvaptan if your body is not able to make urine, you are allergic to Tolvaptan or if you are on certain medicines which interfere with the working of Tolvaptan.

Q. Can I have grapefruit juice while taking Tolvaptan?

No, you should not take grapefruit or grapefruit juice while on Tolvaptan. The reason being, grapefruit or grapefruit juice may increase the levels of Tolvaptan in your blood and your sodium levels may rise too quickly.

Q. What will happen if I take excess of Tolvaptan?

You may need urgent medical attention. Call your doctor or seek emergency service at a nearby hospital. Symptoms of taking too much Tolvaptan may include thirst, dry and flaky skin, sunken eyes, rapid heartbeat, rapid and shallow breathing, very low blood pressure, passing more urine than normal and fainting.

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App

Connect

  • Social Links
  • Want daily dose of health?
Download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.

© 2025 Tata 1mg. All rights reserved. All medicines are dispensed in compliance with the Drugs and Cosmetics Act, 1940 and Drugs and Cosmetics Rules, 1945. We do not process requests for Schedule X and habit forming drugs.