Vitamin D (25-OH)
Understanding Vitamin D (25-OH)
What is Vitamin D (25-OH)?
Vitamin D (25-OH) test monitors the amount of 25-hydroxyvitamin D in your blood. The prevalence of Vitamin D deficiency is quite common across all age groups. If your Vitamin D levels are low you may experience bone pain, muscle weakness, fatigue, and mood changes.
Mild to moderate deficiency is associated with osteoporosis while severe deficiency can cause rickets in children and osteomalacia in adults. There can be seasonal variation in 25 (OH) Vitamin D levels with values being 40-50% lower in winter than in summer. Eating foods containing Vitamin D in addition to taking supplements and proper exposure to sun can help keep your Vitamin D levels within the normal range.
Interpreting Vitamin D (25-OH) results
Interpretations
Low vitamin D level than normal reference range indicates vitamin D deficiency which can be because of less sun exposure, dietary deficiency or due to decreased absorption from the intestine.
High vitamin D level than normal reference range indicates vitamin D intoxication and is usually due to excess supplementation of the vitamin.
Range:
The normal range of vitamin D is measured as nanograms per milliliter (ng/mL) or nmol/L and can vary from lab to lab.
Level |
Reference range (ng/mL) |
Deficiency |
<20 |
Insufficiency |
20-29 |
Sufficiency |
30-100 |
Toxicity |
>100 |
Note:
· There can be seasonal variation in 25 (OH) vitamin D level, with values being 40-50% lower in winter than in summer. It is also influenced by sunlight, latitude, skin pigmentation, sunscreen use, and hepatic function.
· 25 (OH) vitamin D levels can vary with age
· 25 (OH) vitamin D level is increased during pregnancy.