Your doctor will decide the next course of action if there is no improvement seen even after giving ACTEMRA 80 MG INJECTION. ACTEMRA 80 MG INJECTION will prevent inflammation of the lungs but will not cure the damage already done due to the existing disease. Recovery of the lungs takes time to improve. Persistent breathlessness after ACTEMRA 80 MG INJECTION administration requires further evaluation of patients for other lung-related issues (pulmonary intravascular coagulopathy) or heart-related problems (cardiac dysfunctions). Any other bacterial infections that might have occurred should also be treated separately.

Prescription Required

Marketer

Roche Products India Pvt Ltd

SALT COMPOSITION

Tocilizumab (80mg)

Product introduction

ACTEMRA 80 MG INJECTION is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). It reduces swelling in these conditions by blocking TNF alpha.

ACTEMRA 80 MG INJECTION is used to treat joint diseases leading to severe painful swelling and redness of the joints that can lead to difficulty in movement.

Uses of Actemra Injection

Benefits of Actemra Injection

In Treatment of Ankylosing spondylitis

Ankylosing spondylitis is a condition that mainly affects the spine. It causes severe pain and stiffness from the neck to the lower back.
ACTEMRA 80 MG INJECTION acts by lowering the activity of chemicals that causes pain and swelling. ACTEMRA 80 MG INJECTION slows down any damage caused by the disease and reduces the possibility of long-term disability.
ACTEMRA 80 MG INJECTION is a slow-acting medicine so you won’t notice an immediate effect but they’re very effective over a period of time. So it is advisable to take it as prescribed by your doctor.

In Treatment of Rheumatoid arthritis

Rheumatoid arthritis or RA is an autoimmune disorder, in which the immune system starts attacking the lining of your joints. This causes pain and swelling in the joints.

ACTEMRA 80 MG INJECTION helps treat rheumatoid arthritis. It makes the immune system function normally and prevents it from attacking the body. This gives relief from the symptoms such as pain, swelling, and stiffness in the joints. This helps in easy movement and makes you do your daily activities more easily.

You may notice some relief of joint swelling, pain, and stiffness within the first 8 weeks of treatment with ACTEMRA 80 MG INJECTION.

In Treatment of Psoriasis

Psoriasis is a condition where the cells in the body grow too quickly and form scales and dry, itchy patches. They can grow anywhere, but most appear on the elbows, knees, scalp, and lower back. ACTEMRA 80 MG INJECTION reduces the scaly, itchy patches which may develop on different parts of the body. It also reduces dryness associated with Psoriasis and improves skin condition. This helps boost your self-confidence and improves quality of your life. It may take several months to become fully effective. Use it exactly and for as long as it is prescribed to get the most benefit.

In Treatment of Ulcerative colitis

Ulcerative colitis is a condition that causes redness and swelling in the large intestine and the rectum (lower part of large intestine). This can cause bleeding, frequent passing of stool and stomach pain. ACTEMRA 80 MG INJECTION reduces the pain and swelling and gives you relief from these symptoms. It reduces the discomfort and helps you live your life normally.
ACTEMRA 80 MG INJECTION if taken as prescribed can prevent the return of ulcerative colitis flare (return or worsening of your symptoms). Drink plenty of fluids while taking it to make sure you stay hydrated.

In Treatment of Crohn’s disease

Crohn's disease is a condition that causes redness and swelling in any part of the digestive system from mouth to the anus. It can cause severe stomach pain.
ACTEMRA 80 MG INJECTION works by blocking chemicals causing pain and swelling. Thereby giving relief and helping you to live a normal life. This medicine is given as an injection. You should always take it as it has been prescribed for you.

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Side effects of Actemra Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actemra

Headache
High blood pressure
Upper respiratory tract infection
Injection site reactions (pain, swelling, redness)

How to use Actemra Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

SAFE

Consuming alcohol with ACTEMRA 80 MG INJECTION does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

ACTEMRA 80 MG INJECTION may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

ACTEMRA 80 MG INJECTION is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

ACTEMRA 80 MG INJECTION may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

ACTEMRA 80 MG INJECTION should be used with caution in patients with kidney disease. Dose adjustment of ACTEMRA 80 MG INJECTION may be needed. Please consult your doctor.
Limited information is available on the use of ACTEMRA 80 MG INJECTION in patients with moderate to severe kidney disease. No dose adjustment is required in patients with mild kidney disease.

Liver

CAUTION

ACTEMRA 80 MG INJECTION should be used with caution in patients with liver disease. Dose adjustment of ACTEMRA 80 MG INJECTION may be needed. Please consult your doctor.
Use of ACTEMRA 80 MG INJECTION is not recommended in patients with active liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

ACTEMRA 80 MG INJECTION is given as a drip (intravenous infusion) or as an injection directly into a vein.
You may be asked for regular blood tests to check blood counts, cholesterol level and liver functioning during the treatment.
It might make you feel dizzy. If this happens, avoid driving or operating on machinery.
It makes it hard to fight with an infection. Inform your doctor if you notice fever, cough or stomach pain.
Inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
Do not stop taking medicine without talking to your doctor first.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

Therapeutic Class

abcde

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics

Patient concerns

Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time

Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest.

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist

Suffering from severe lower back pain since 6 years. As per MRI it is lumbar spondylosis,but Doctor told that it is one of the types of arthritis in which bridge is getting formed on spine Is there any permanent solution .at present taking Sazo 500 twice a day

Dr. Akshat Goel

Orthopaedics

It's called Ankylosing spondylitis". no permanent cure for this All you need to do is to exercise each and every joint of your body regularly "Along with the medication

FAQs

Who should be treated with ACTEMRA 80 MG INJECTION?

ACTEMRA 80 MG INJECTION should be given for treating patients suffering from moderate to severe Covid-19 infection who have persistent reduction in their oxygen levels (a condition called hypoxia) that continues to get worse. The hypoxia may continue to get worsened even after 24 to 48 hours of treatment with corticosteroids and supportive care.

Is ACTEMRA 80 MG INJECTION recommended for all Covid-19 patients? If not, why?

No, ACTEMRA 80 MG INJECTION is not recommended for all Covid-19 patients. This is because ACTEMRA 80 MG INJECTION has its own potential health hazards. ACTEMRA 80 MG INJECTION can lead to persistent serious infection and prolonged multiplication and shedding of the virus causing infection, so, it must be given only if the benefits outweigh the risks involved.

What are the side effects of ACTEMRA 80 MG INJECTION?

The potential side effects of ACTEMRA 80 MG INJECTION include anaphylaxis (serious allergic reaction) with infusion, transaminitis (very high levels of liver enzymes due to which they start moving into the bloodstream), leukopenia (a condition where a person has reduced white blood cells and hence increased risk for infections) and neutropenia (a condition where a person has abnormally low number of cells called neutrophils, that fight infections in our body). Some other side effects are risk of serious bacterial infections, viral infections and reactivation of tuberculosis (TB) virus.

Who should not be given ACTEMRA 80 MG INJECTION?

ACTEMRA 80 MG INJECTION should not be given to patients who have or ever had abnormal levels of liver enzymes (transaminitis), platelet counts (<50000), or if they have TB, or any active bacterial or viral infection. The use of ACTEMRA 80 MG INJECTION is contraindicated in pregnancy and breastfeeding mothers too, owing to its risk of developing serious complications.

What to do if there is no improvement seen after giving ACTEMRA 80 MG INJECTION too?

Your doctor will decide the next course of action if there is no improvement seen even after giving ACTEMRA 80 MG INJECTION. ACTEMRA 80 MG INJECTION will prevent inflammation of the lungs but will not cure the damage already done due to the existing disease. Recovery of the lungs takes time to improve. Persistent breathlessness after ACTEMRA 80 MG INJECTION administration requires further evaluation of patients for other lung-related issues (pulmonary intravascular coagulopathy) or heart-related problems (cardiac dysfunctions). Any other bacterial infections that might have occurred should also be treated separately.

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Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

HLA - B27, PCR

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

Related ayurvedic ingredients

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Shallaki

Isabgol

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Medscape. Tocilizumab. [Accessed 02 Apr. 2019] (online) Available from:
Tocilizumab. South San Francisco, California: Genentech, Inc. [Accessed 30 Jan. 2019] (online) Available from:

Marketer details

Name: Roche Products India Pvt Ltd

Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Country of origin: India

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ACTEMRA 80 MG INJECTION