Adoxi 20mg Injection Combipack is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.

Adoxi 20mg Injection Combipack

Uses of Adoxi Injection

Benefits of Adoxi Injection

In Breast cancer

Adoxi 20mg Injection Combipack helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Adoxi 20mg Injection Combipack kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Adoxi 20mg Injection Combipack helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Cancer of head and neck

Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Adoxi 20mg Injection Combipack kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but it has some bothersome side effects. Therefore, you should discuss the risks and benefits with your doctor.

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Side effects of Adoxi Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Adoxi

Breathlessness
Constipation
Edema (swelling)
Infection
Loss of appetite
Muscle pain
Nail disorder
Pain
Weakness

How to use Adoxi Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Adoxi 20mg Injection Combipack.

Pregnancy

CONSULT YOUR DOCTOR

Adoxi 20mg Injection Combipack is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Adoxi 20mg Injection Combipack is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Adoxi 20mg Injection Combipack alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Adoxi 20mg Injection Combipack is safe to use in patients with kidney disease. No dose adjustment of Adoxi 20mg Injection Combipack is recommended.

Liver

CAUTION

Adoxi 20mg Injection Combipack should be used with caution in patients with liver disease. Dose adjustment of Adoxi 20mg Injection Combipack may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Adoxi 20mg Injection Combipack

₹2690.0/Injection

Doceaqualip 20mg Injection

Intas Pharmaceuticals Ltd

₹5178/injection

92% costlier

Taxotere 20mg Injection

Emcure Pharmaceuticals Ltd

₹5529/injection

106% costlier

Zytax 20mg Injection

Zydus Cadila

₹2890/injection

7% costlier

Docetere 20mg Injection

Dr Reddy's Laboratories Ltd

₹3840.8/injection

43% costlier

Taxocare 20mg Injection

Intas Pharmaceuticals Ltd

₹3042.08/injection

13% costlier

View all substitutes

Quick tips

Adoxi 20mg Injection Combipack is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.
Do not take Adoxi 20mg Injection Combipack if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
It may cause side effects such as swelling of hands, lips, and weight gain. To reduce these side effects your doctor may suggest some medication along with this medicine called Corticosteroids.
Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.

Fact Box

Chemical Class

Taxanes Derivatives

Habit Forming

Therapeutic Class

abcde

Action Class

Antimicrotubule agents- Taxanes

Patient concerns

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

FAQs

Does Adoxi 20mg Injection Combipack cause weight gain?

Yes, Adoxi 20mg Injection Combipack may cause weight gain. It may occur due to fluid retention which may initially make your feet swell and then gradually it will spread to the whole body. Call your doctor immediately if you notice swelling of feet.

How long do I have to take Adoxi 20mg Injection Combipack?

You should continue to take Adoxi 20mg Injection Combipack as long as your doctor advises you. The duration of treatment varies with the type of cancer you have and other factors like your response to treatment. You should usually receive your infusion once every 3 weeks.

Can I drink alcohol while on Adoxi 20mg Injection Combipack?

Adoxi 20mg Injection Combipack injection contains alcohol because of which you may experience confusion, stumbling, becoming very sleepy, or feeling like you are drunk. This may impair your ability to drive or use machinery right after receiving it. Hence, you should avoid alcohol during Adoxi 20mg Injection Combipack therapy, as it may affect you adversely.

What is Adoxi 20mg Injection Combipack used for?

Adoxi 20mg Injection Combipack is commonly used for breast cancer, certain types of lung cancer, prostate, stomach, and head and neck cancers. It works by restricting cells from growing and multiplying.

Is Adoxi 20mg Injection Combipack available in pill form?

No, Adoxi 20mg Injection Combipack injection comes as a liquid to be given intravenously (into a vein) by a doctor or nurse in a hospital or clinic. It is usually given over 1 hour once every 3 weeks.

What blood tests are required before administration of Adoxi 20mg Injection Combipack?

Your doctor will ask you to get blood tests every time you have a scheduled dose of Adoxi 20mg Injection Combipack. You may be asked to have blood tests, such as hemogram and liver function tests, to ensure that you have enough blood cells and that your liver is functioning well enough to receive Adoxi 20mg Injection Combipack. In case of white blood cells disturbances, you may experience associated fever or infections.

Is hair loss caused by Adoxi 20mg Injection Combipack irreversible?

Hair loss is a common side effect of Adoxi 20mg Injection Combipack. Normal hair growth may resume after stopping Adoxi 20mg Injection Combipack. However, in some cases there is permanent hair loss. Consult your doctor if you have any concerns regarding hair loss.

Why is dexamethasone used with Adoxi 20mg Injection Combipack?

Adoxi 20mg Injection Combipack may cause fluid retention (swelling in the hands, feet, ankles and legs) as well as severe hypersensitivity reactions. To control such possibilities from occurring all patients are given corticosteroids (dexamethasone) for 3 days starting 1 day prior to Adoxi 20mg Injection Combipack administration. In case of prostate cancer (metastatic castration-resistant), the recommended regimen is oral dexamethasone given at 12 hours, 3 hours, and 1 hour before the Adoxi 20mg Injection Combipack infusion.

What type of drug is Adoxi 20mg Injection Combipack?

Adoxi 20mg Injection Combipack belongs to the group of anti-cancer medicines called taxoids. It works by stopping the growth and spread of cancer cells.

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Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Related ayurvedic ingredients

Olive oil

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 422-23.
Docetaxel Injection. Unterach, Austria: EBEWE Pharma Ges.m.b.H. Nfg.KG; 1996 [revised Mar. 2012. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Docetaxel. [Updated 2019 Jun 30]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Adley Formulations

Address: Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India

Country of origin: India

MRP

₹2690

Inclusive of all taxes

0.5 ml in 1 vial

SOLD OUT

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