Bisotidine 400mg Tablet is an antacid. It reduces the amount of acid produced by your stomach. It is used to treat and prevent heartburn, indigestion and other symptoms caused by too much acid in the stomach. It is also used to treat and prevent stomach ulcers, reflux disease and some other rare conditions.

Bisotidine 400mg Tablet relieves heartburn and helps in healing ulcers.

Uses of Bisotidine Tablet

Heartburn
Gastroesophageal reflux disease (Acid reflux)
Peptic ulcer disease

Benefits of Bisotidine Tablet

In Heartburn

Heartburn is a burning feeling in your chest caused by stomach acids travelling back up towards your throat and mouth (acid reflux). It happens because a muscle above your stomach relaxes too much and allows stomach contents and acid to come back up into your esophagus and mouth. This can be a symptom of indigestion (dyspepsia). Bisotidine 400mg Tablet works by reducing the amount of acid your stomach makes and relieves the pain associated with heartburn and indigestion.You should take it exactly as it is prescribed by your doctor for it to be effective. Some simple lifestyle changes can help stop or reduce heartburn. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3–4 hours of going to bed.

In Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (GERD) is a chronic condition that is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Bisotidine 400mg Tablet reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

In Peptic ulcer disease

Bisotidine 400mg Tablet is used to treat peptic ulcers. It reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear. It may also be prescribed to prevent stomach ulcers from forming by reducing the amount of acid.

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Side effects of Bisotidine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bisotidine

Headache
Dizziness
Diarrhea
Muscle pain
Skin rash
Tiredness

How to use Bisotidine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bisotidine 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Bisotidine Tablet works

Bisotidine 400mg Tablet is a histamine H2 receptor antagonist. It works by reducing the amount of acid produced in the stomach which helps relieve acid-related indigestion and heartburn.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Bisotidine 400mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Bisotidine 400mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Bisotidine 400mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

SAFE

Bisotidine 400mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Bisotidine 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Bisotidine 400mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Bisotidine 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bisotidine 400mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Bisotidine 400mg Tablet

₹3.25/Tablet

Cimetiget 400mg Tablet

Franco-Indian Pharmaceuticals Pvt Ltd

₹1.48/tablet

54% cheaper

Tymidin 400mg Tablet

Abbott L

₹1.4/tablet

57% cheaper

Ulciban 400mg Tablet

Torrent Pharmaceuticals Ltd

₹2.56/tablet

21% cheaper

C Met 400mg Tablet

Cyper Drugs & Pharmaceuticals Pvt Ltd

₹1.4/tablet

57% cheaper

Neotid 400mg Tablet

Neon Laboratories Ltd

₹2.56/tablet

21% cheaper

Quick tips

Take Bisotidine 400mg Tablet before going to bed if you are taking this medicine once a day. It is very effective in controlling stomach acid that is released when you are asleep.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Inform your doctor if you do not feel better after taking Bisotidine 400mg Tablet for 2 weeks as you may be suffering from some other problems.
Inform your doctor if you have ever been diagnosed with kidney disease as dose of your medicine may need to be adjusted.
Inform your doctor about any other medications or supplements that you are taking because Bisotidine 400mg Tablet can interfere with the working of other medications.
Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class

Imidazoles Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

H2 Receptor Blocker

Patient concerns

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

Having problem of acid reflux disease with throat infection and pain in right side of abdomen

Dr. Aanchal Maheshwari

Ayurveda

take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,,

Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen

Dr. Saurav Arora

Homeopathy

Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly,

FAQs

How can Bisotidine 400mg Tablet cause gynecomastia?

Bisotidine 400mg Tablet causes gynecomastia (enlarged breasts of males) by decreasing the male hormone (testosterone) levels and blocking the sensitivity of the target areas on which testosterone acts. However, the breast enlargement is not bothersome. Please consult your doctor if this worries you.

Can I take Bisotidine 400mg Tablet with loperamide?

Bisotidine 400mg Tablet can decrease the metabolism of Loperamide, increase its blood levels. This can in turn increase the effects and side effects of Loperamide. So, consult your doctor prior to taking both the medicines together as your dose of Loperamide may need to be decreased.

Is there any vitamin and mineral loss when Bisotidine 400mg Tablet is taken?

Bisotidine 400mg Tablet is not known to cause vitamin and mineral loss or deficiency. However, Bisotidine 400mg Tablet belongs to the class of H2 receptor blocker which can decrease vitamin B12 absorption and cause its deficiency as reported in some studies especially when used for more than two years.

Is Bisotidine 400mg Tablet an antacid?

No, Bisotidine 400mg Tablet is not an antacid as it does not neutralize the acids of the stomach rather it works by decreasing the production of the acid.

Are there any withdrawal symptoms associated with the use of Bisotidine 400mg Tablet?

Clinical studies or reports so far have not reported any withdrawal symptoms when the patient stops taking Bisotidine 400mg Tablet and this suggests that Bisotidine 400mg Tablet has no addictive potential.

Can I take Bisotidine 400mg Tablet with antacids?

Antacids and Bisotidine 400mg Tablet both can be taken at the same time as they are not known to affect each other’s action. However, both Bisotidine 400mg Tablet and antacids help in decreasing the acidity and use of more than one drug for the same effect is not advisable unless absolutely necessary.

Can I take Bisotidine 400mg Tablet with coffee?

There are no reports of any harmful effects of taking Bisotidine 400mg Tablet along with coffee. However, Bisotidine 400mg Tablet can decrease the breakdown of coffee and increase its effects. Also, coffee is a gastric stimulant and can increase acid secretion and aggravate your underlying condition.

How is Omeprazole better than Bisotidine 400mg Tablet?

Omeprazole is a proton pump inhibitor and Bisotidine 400mg Tablet is an H2 receptor blocker. They act in different ways but both decrease the acid production in the stomach. However, according to some studies, omeprazole is more potent, longer acting, and has fewer side effects when compared to Bisotidine 400mg Tablet.

Why should Bisotidine 400mg Tablet be taken at bedtime?

Bisotidine 400mg Tablet can be given as a single daily dose or as multiple daily doses depending on your condition. When given in a single dose, it is preferred that you should take it before going to bed as it is very effective in decreasing nighttime acid secretion and a fixed time will help you to remember to take the medicine.

Does Bisotidine 400mg Tablet work for molluscum contagiosum?

Oral Bisotidine 400mg Tablet has been seen to be effective in treating molluscum in children. However, this is not an approved indication for its use. Please consult your doctor before taking it for this condition.

Why does Bisotidine 400mg Tablet increase the action of opiates?

Bisotidine 400mg Tablet increases the action of an opioid like substances by inhibiting enzymes which are responsible for the breakdown of opiates. Due to a decrease in the breakdown, opioid levels increase in the body and hence their action is also increased.

Is Bisotidine 400mg Tablet available over the counter?

No, Bisotidine 400mg Tablet is not available as an over-the-counter medication. It is a prescription medicine and is available only when prescribed by a physician.

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References

Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, BC Knollmann, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 29 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cimetidine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Country of origin: India

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