Coenac 400 Solution is an antidote medication. It is used in the treatment of paracetamol overdose (when you may have taken too much paracetamol medicine). It protects your liver and helps to reduce the extent of the injury.

Coenac 400 Solution is used as mucolytic

Uses of Coenac Injection

Treatment of Paracetamol toxicity

Benefits of Coenac Injection

In Treatment of Paracetamol toxicity

Coenac 400 Solution is an antidote medicine that prevents serious side effects if a person has taken more than the normal or recommended amount of a medicine called paracetamol which leads to an overdose. Initially, there may be mild gastrointestinal symptoms like nausea, vomiting, stomach pain, irritability, etc. But, if left untreated, paracetamol overdose may cause serious liver damage, which may even lead to liver failure. Rarely, an excessive overdose may lead to a coma. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit from this medication.

Side effects of Coenac Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Coenac

Rash
Red spots or bumps
Flushing (sense of warmth in the face, ears, neck and trunk)
Itching

How to use Coenac Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Coenac Injection works

Coenac 400 Solution is an antidote for paracetamol poisoning. It works by increasing the level of glutathione, an antioxidant that neutralises the toxic products of paracetamol.

Safety advice

Alcohol

SAFE

Consuming alcohol with Coenac 400 Solution does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

Coenac 400 Solution is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Coenac 400 Solution is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Coenac 400 Solution does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Coenac 400 Solution is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Coenac 400 Solution may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Coenac 400 Solution is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Coenac 400 Solution may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Coenac 400 Solution

₹47.11/Injection

Mucyst Injection

Neon Laboratories Ltd

₹48.5/injection

3% costlier

Mucosys 400mg Injection

United Biotech Pvt Ltd

₹59.5/injection

26% costlier

Mucotroy 400mg Injection

Troikaa Pharmaceuticals Ltd

₹45.52/injection

3% cheaper

Nacel 400mg Injection

Celon Laboratories Ltd

₹20.95/injection

56% cheaper

MUCOMELT 400 MG INJECTION

Venus Remedies Ltd

₹45.54/injection

3% cheaper

Quick tips

Coenac 400 Solution is used for the treatment of paracetamol overdose (when you may have taken too much paracetamol).
It protects the liver from damage by the high levels of paracetamol.
It is very effective when given during the first 8 hours following paracetamol overdose. The effectiveness is reduced with time but it can still help when given within 24 hours.

Fact Box

Chemical Class

N-Acylated Alpha Amino Acids

Habit Forming

Therapeutic Class

OTHERS

Action Class

Acetylcysteine -Mucolytic

Patient concerns

Ferrous sulphate tablets toxicity

Dr. Megha Gupta

Obstetrics and Gynaecology

There is no toxicity as such. Please be specific in what respect are you asking.

Diazepam toxicity about 45 tablets

Dr. Ambrish Dharmadhikari

Psychiatry

Rush immediately to emergency services

Sir rahul yadav paediatric prefer a medicine ARACHITOL SACHET. but that is not availabale any medical & online also please can you prefer any other medicine for my female child. She is so slim age is 18 months still she is not walking properly. Weght is 8 kg only. I also give her calcimax p and zincovit

Dr. Gopal Samdani

Paediatrics

Please do Vit D test and if needed then only give supplement as excess can cause toxicity

FAQs

Is Coenac 400 Solution good for liver?

Yes, Coenac 400 Solution is good for the liver. It improves liver function and activity in patients with non-alcoholic fatty liver disease. It also prevents liver from toxic agents which can damage the liver. Additionally, it also prevents liver from damage in cases of drug overdose like paracetamol, etc.

Does Coenac 400 Solution affect blood pressure?

Yes, Coenac 400 Solution by acting through various mechanism prevents the rise of blood pressure and maintains the normal functioning of the body. There are reports which show that Coenac 400 Solution can prevent damage to the inner lining of the blood vessels of the body, which will maintain the elasticity and vitality of the blood vessels. It also increases the antioxidants levels in the body hence preventing the body from oxidative damage.

Does Coenac 400 Solution help anxiety?

There is no concrete evidence that Coenac 400 Solution can be used alone in the treatment of anxiety disorder. However, in some reports, it is shown that Coenac 400 Solution provides benefit by acting as an antioxidant. This property prove to be beneficial in psychiatric and neurological conditions when added to the normal treatment of the particular disorder. Do not take this medication without consulting your doctor. Contact the doctor for any query if you feel anxious.

Is Coenac 400 Solution good for kidneys?

Yes, Coenac 400 Solution is beneficial when used in patients with impaired kidney functions. It is also used to prevent or minimize the damage caused by the use of contrast during investigations like CT scan or other body scans.

Does Coenac 400 Solution need to be refrigerated?

Unopened vials of Coenac 400 Solution should be stored at room temperature. Once the medicine is opened and diluted it should be used within 3 hours as per the directions of the physician. It should not be stored above 25ºC. Once opened, the vials should be stored in refrigeration and if unused then should be discarded after 96 hours.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 13-15.
Acetylcysteine (N-Acetylcysteine). In: Hitchings A, Lonsdale D, Burrage D, et al., editors. The Top 100 Drugs: Clinical Pharmacology and Practical Pescribng. Churchil Livingstone Elsevier; 2015.
Acetylcysteine. Romford, Essex: Martindale Pharma; 2004 [revised 23 Feb. 2017]. [Accessed 01 Apr. 2019] (online) Available from:
Acetylcysteine. Nashville, Tennessee: Cumberland Pharmaceuticals Inc.; 2004 [revised Jun. 2013]. [Accessed 31 Jan. 2019] (online) Available from:
Acetylcysteine Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2018. [Accessed 09 Jun, 2023] (online) Available from:

Marketer details

Name: Koye Pharmaceuticals Pvt ltd

Address: A-10, 3rd Floor, Art Guild House, Phoenix Market City Annexe, LBS Marg, Kurla (West), Mumbai - 400070

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.