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Product introduction

Equisulin M 50 Injection is a combination of two medicines, an intermediate-acting and a short-acting type of insulin. It is used in the treatment of diabetes mellitus (type 1 and 2) to improve blood sugar control both in adults and children. It helps maintain the blood sugar levels in diabetic patients.

Equisulin M 50 Injection is normally prescribed along with other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Don’t stop taking it unless your doctor tells you to.

It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.

The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it's important to always inject the correct dose of medicine only, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Some people gain weight while taking insulin.  You may also notice a rash, edema (swelling), or itching while taking this medicine.

Do not use this medicine when you have low blood glucose levels (hypoglycemia). Tell your doctor if you’ve ever had kidney, liver or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.

Uses of Equisulin M Injection

Benefits of Equisulin M Injection

In Diabetes

Equisulin M 50 Injection contains an intermediate-acting and a short-acting type of insulin. Together, they ensure rapid and consistent sugar control that helps control blood sugar levels for an entire day. It is given as an injection and your doctor or nurse will train you on the correct way to inject it. Managing blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Equisulin M Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Equisulin M

  • Hypoglycemia (low blood glucose level)
  • Injection site reactions (pain, swelling, redness)
  • Weight gain

How to use Equisulin M Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Equisulin M Injection works

Equisulin M 50 Injection is a combination of two insulin preparations: Insulin Isophane / NPH and Human Insulin / Soluble Insulin. Insulin Isophane / NPH has a prolonged duration of action, while human insulin / soluble insulin has a fast onset of action. Together, they ensure rapid and consistent sugar control by facilitating reuptake of sugar in muscle and fat cells and suppressing the production of sugar in the liver.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Equisulin M 50 Injection.
Pregnancy
SAFE IF PRESCRIBED
Equisulin M 50 Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Equisulin M 50 Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Equisulin M 50 Injection should be used with caution in patients with kidney disease. Dose adjustment of Equisulin M 50 Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver
CAUTION
Equisulin M 50 Injection should be used with caution in patients with liver disease. Dose adjustment of Equisulin M 50 Injection may be needed. Please consult your doctor.
Regular monitoring of glucose levels is recommended for dose adjustment.

What if you forget to take Equisulin M Injection?

If you have missed a dose of Equisulin M 50 Injection, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Equisulin M 50 Injection
₹266.88/Injection
₹258.96/injection
3% cheaper
₹290.15/injection
9% costlier
Huminsulin 50/50 Injection 100IU/ml
Eli Lilly and Company India Pvt Ltd
₹383.25/injection
44% costlier
₹318.5/injection
19% costlier
₹471.87/injection
77% costlier

Quick tips

  • Take it 15 minutes before a meal or within 20 minutes after starting a meal.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites such as skin of the upper arms, thighs, or buttocks. After injection, the site of injection should not be massaged.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Change to another type or brand of insulin should be done under strict medical supervision as it may require a change in dosage.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Do not share your insulin device with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.
  • Opened vials / cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator  (2°C–8°C).

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

Patient concerns

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Several diabetes ,, highest diabetes
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
Please explain diabetes and diabetes diet
Dr. Sanjay Bhatt
Physician
Diabetes is a medical condition in which sugar, or glucose, levels build up in your bloodstream. There?s not enough insulin to move the sugar into your cells, which are where the sugar is used for energy. This causes your body to rely on alternative energy sources in your tissues, muscles, and organs. This is a chain reaction that can cause a variety of symptoms. Type 2 diabetes can develop slowly. The symptoms may be mild and easy to dismiss at first. The early symptoms may include: constant hunger a lack of energy fatigue weight loss excessive thirst frequent urination dry mouth itchy skin blurry visionDiet is an important tool to keep your heart healthy and blood sugar levels within a safe and healthy range. It doesn?t have to be complicated or unpleasant. The diet recommended for people with type 2 diabetes is the same diet just about everyone should follow. It boils down to a few key actions: Eat meals and snacks on schedule. Choose a variety of foods that are high in nutrition and low in empty calories. Be careful not to overeat. Read food labels closely.
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FAQs

Can I drink alcohol while taking Equisulin M 50 Injection?

No, it is not safe to drink alcohol while using Equisulin M 50 Injection. Drinking alcohol while using this medicine may lower your blood sugar levels and cause unexpected hypoglycemia.

What are the instructions for storage and disposal of Equisulin M 50 Injection?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Which is the best area to inject Equisulin M 50 Injection?

Equisulin M 50 Injection is to be injected under the skin (subcutaneously). The best areas to give Equisulin M 50 Injection are your stomach, upper thigh, upper arm or buttocks.

What are the symptoms of high blood sugar?

Symptoms of high blood sugar include frequent urination, increased thirst, fatigue, nausea, vomiting, shortness of breath, stomach pain, fruity breath odor, dry mouth and a fast heartbeat.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. European Medicine Agency. Insulin Isophane/NPH+Human Insulin/Soluble Insulin; 2002 [revised Nov. 2013]. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Isophane. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2014 [revised 30 Jul. 2018]. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Human Insulin. Gatwick, West Sussex: Novo Nordisk Limited; 2002 [revised Mar. 2018]. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Mixtard [Summary of Product Characteristics]. Bagsværd, Denmark; Novo Nordisk A/S; 2021. [Accessed 13 Oct. 2021] (online) Available from: External Link
  5. Humulin [FDA Prescribing Information]. Indianapolis, USA; Lilly USA, LLC.; 2018. [Accessed 13 Oct. 2021] (online) Available from:External Link
  6. Medscape. Insulin Isophane/NPH/ Human Insulin/Soluble Insulin. [Accessed 08 Apr. 2019] (online) Available from:External Link
Country of origin: India

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