Ethi 250mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.

It is an antibiotic.

Uses of Ethi Tablet

Tuberculosis (TB)

Benefits of Ethi Tablet

In Tuberculosis (TB)

Ethi 250mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Ethi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ethi

Loss of appetite
Nausea
Vomiting
Gastric irritation
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Weakness
Depression
Sleepiness

How to use Ethi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ethi 250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Ethi 250mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Ethi 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Ethi 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Ethi 250mg Tablet may cause side effects which could affect your ability to drive.
Ethi 250mg Tablet may cause side effects such as drowsiness or a headache, that can impair your ability to drive.

Kidney

SAFE IF PRESCRIBED

Ethi 250mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ethi 250mg Tablet may not be needed in these patients. Please consult your doctor.
Dose adjustment may be needed in patients with end stage kidney disease.

Liver

CAUTION

Ethi 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Ethi 250mg Tablet may be needed. Please consult your doctor.
Use of Ethi 250mg Tablet is not recommended in patients with the severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

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Quick tips

Ethi 250mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
It has to be taken for several months in order for it work properly (usually 6 months).
Take it with food to avoid stomach upset.
It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
Avoid consuming alcohol while taking this medication.
Do not stop taking Ethi 250mg Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Fact Box

Chemical Class

Nicotinic acid derivatives

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycobacterial cell wall inhibitors-Ethambutol

Patient concerns

My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???

Dr. Rahul Yadav

Paediatrics

Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.

Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?

Dr. Anshum Aneja Arora

Pulmonology

If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis

Doctor asked me to do TB GOLD test. But there is no lab test on 1mg with so name. Finally I searched for tuberculosis test and I found two test. 1 is Mycobacterium tuberculosis and other 1 is Mycobacterium tuberculosis sputum. Kindly tell me which test is to be selected and proceeded further.

Dr. Gopal Samdani

Paediatrics

Please follow your doctors advise as he has clinical examination data with him. He can advise you for place where you can do TB gold

FAQs

What is Ethi 250mg Tablet? What is it used for?

Ethi 250mg Tablet is an antibiotic. It is used as a second-line medicine in combination with other anti-tuberculosis medicines for the treatment of all forms of tuberculosis caused by Mycobacterium tuberculosis.

Why is Ethi 250mg Tablet called a second line drug?

Tuberculosis (TB) is a difficult infection to treat and when it is detected for the first time, first-line drugs are used. Generally, the appropriate use of first-line drugs (e.g. isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin) can effectively cure TB. But, if the patient does not respond to first-line medicines, then second-line medicines (e.g. Ethi 250mg Tablet, kanamycin, ciprofloxacin, etc.) are used. Second-line medicines have more side effects and are the second choice in terms of effectiveness.

Are there any precautions that I should take while taking Ethi 250mg Tablet so that I respond to the treatment?

It is very important that you take the medicine exactly as directed by your doctor. Your doctor will prescribe at least two more medicines to be taken with Ethi 250mg Tablet. Take all the prescribed medicines as per the instructions and do not miss or stop the treatment on your own. Missing doses and stopping the treatment without consulting the doctor are the major causes of treatment failure and drug resistance (not responding to the medication).

For how long do I need to take Ethi 250mg Tablet?

Your doctor will decide the duration of your treatment depending upon your response to the treatment. The doctor will observe your maximum improvement by evaluating you clinically as well as your blood tests.

Why has my doctor asked me to get blood tests done regularly?

The blood tests are done to check if your liver is functioning properly or not, since Ethi 250mg Tablet may affect your liver. Ethi 250mg Tablet can also alter your blood glucose levels and thyroid hormone levels. Therefore, monitoring is required.

What are the symptoms which are suggestive of liver toxicity caused by Ethi 250mg Tablet?

If you develop symptoms such as loss of appetite, nausea, jaundice (yellowing of the skin and eye white), dark urine, discolored stools, pain and tenderness in the upper right abdomen, inform your doctor immediately. These could be the signs of liver toxicity.

Is it necessary to take pyridoxine with Ethi 250mg Tablet?

Pyridoxine is vitamin B6 that helps to prevent nerve damage, which may occur with the use of Ethi 250mg Tablet. The symptoms of nerve damage are numbness, tingling, or pain in your hands or feet.

My friend is taking Ethi 250mg Tablet and other medicines for TB. I have noticed that sometimes she acts very aggressively. Is it because of the disease or the treatment?

These changes could be due to Ethi 250mg Tablet or other medicines that she is taking for TB. Ethi 250mg Tablet may cause depression, confusion, aggression, abnormal thinking, and even hallucinations. You should speak to her family or doctor and help her out.

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Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1561-562.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 513-14.
Ethionamide. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2016. [Accessed 19 Jun. 2019] (online) Available from:
Drugs.com. Ethionamide. [Accessed 01 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:

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