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Janumet 50 mg/500 mg Tablet

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Introduction of Janumet Tablet

Janumet 50 mg/500 mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chances of having a heart attack or stroke.

Janumet 50 mg/500 mg Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It provides better control of blood sugar when single therapy is not effective and reduces both fasting and postmeal sugar levels. It should be used along with a proper diet and exercise for maximum effect. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level) as a side effect.

Benefits of Janumet Tablet

In Treatment of Type 2 diabetes mellitus

Janumet 50 mg/500 mg Tablet is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.

Side effects of Janumet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Janumet

  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Vomiting
  • Diarrhea
  • Decreased appetite
  • Abdominal bloating
  • Upper respiratory tract infection

How to use Janumet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Janumet 50 mg/500 mg Tablet is to be taken with food.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Janumet 50 mg/500 mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Janumet 50 mg/500 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Janumet 50 mg/500 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Janumet 50 mg/500 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Janumet 50 mg/500 mg Tablet may be needed. Please consult your doctor.
Use of Janumet 50 mg/500 mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
UNSAFE
Janumet 50 mg/500 mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Janumet Tablet?

If you miss a dose of Janumet 50 mg/500 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Janumet 50 mg/500 mg Tablet
₹23.0/Tablet
Istamet 50mg/500mg Tablet
Sun Pharmaceutical Industries Ltd
₹3.8/tablet
83% cheaper
Sepamet-XR 50mg/500mg Tablet
Taj Pharma India Ltd
₹24.5/tablet
7% costlier

Quick tips

Janumet Tablet

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • Take it with food to lower your chance of having an upset stomach.
  • Take it in addition to regular exercise and healthy diet to lower levels of blood sugar.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Janumet 50 mg/500 mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

Patient concerns

Patient concerns

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I am a diabetic patient, my pp is 417 & I take amaryl 2 & cetapin 1000 , but my blood sugar didn't control , what I doing this position?
Dr. Sanjay Bhatt
Physician
Start tab janumet 50/500
Dear Dr. Is there any substitute for Janumet 50/500. Volibo 0.2 mg tablets.
Dr. Sanjay Bhatt
Physician
Needs to see the patient as examine, investigate and complete medical history needed for substitute medicine. So discuss with your doctor or visit our clinic
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User feedback


FAQs

Janumet Tablet

Q. What is Janumet 50 mg/500 mg Tablet?

Janumet 50 mg/500 mg Tablet is a combination of two medicines: Sitagliptin and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.

Q. Can the use of Janumet 50 mg/500 mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Janumet 50 mg/500 mg Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems as a result of which the patient can feel tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Q. What are the possible side effects of Janumet 50 mg/500 mg Tablet?

The use of Janumet 50 mg/500 mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effect like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Are there any specific conditions in which Janumet 50 mg/500 mg Tablet should not to be taken?

The use of Janumet 50 mg/500 mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am taking Janumet 50 mg/500 mg Tablet?

No, it is not safe to alcohol along with Janumet 50 mg/500 mg Tablet, as it can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Janumet 50 mg/500 mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Janumet 50 mg/500 mg Tablet lead to lactic acidosis?

Yes, the use of Janumet 50 mg/500 mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by the increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sitagliptin + Metformin and immediately consult your doctor.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sitagliptin/metformin hydrochloride. Haarlem, The Netherlands: Merck Sharp & Dohme BV; 2018. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Sitagliptin / metformin hydrochloride. London, UK: European Medicine Agency; 2013. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Mayo Clinic. Sitagliptin and Metformin. [Accessed 08 Apr. 2019 ] (online) Available from:External Link
  4. Sitagliptin and metformin hydrochloride. [Accessed 08 Apr. 2019] (online) Available from:External Link
  5. Sitagliptin and Metformin hydrochloride [Product Monograph]. Kirkland, Canada: Merck Canada Inc.; 2021. [Accessed 20 Oct. 2021] (online) Available from:External Link
  6. Sitagliptin and Metformin hydrochloride [Product Monograph]. Kirkland, Canada: Merck Canada Inc.; 2017. [Accessed 20 Oct. 2021] (online) Available from:External Link

Marketer details

Name: MSD Pharmaceuticals Pvt Ltd
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Country of origin: India
Expires on or after: August, 2024

A licensed vendor partner from your nearest location will deliver Janumet 50 mg/500 mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

MRP
345
Inclusive of all taxes
15.0 tablets in 1 strip
Add to cart
Cash on delivery available

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