Lortinib 100mg Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.

Lortinib 100mg Tablet is used to treat different types of cancer

Uses of Lortinib Tablet

Benefits of Lortinib Tablet

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Lortinib 100mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Pancreatic cancer

Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Lortinib 100mg Tablet helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.

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Side effects of Lortinib Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lortinib

Abdominal pain
Bone pain
Breathlessness
Constipation
Cough
Diarrhea
Fatigue
Fever
Infection
Muscle pain
Nausea
Rash
Stomatitis (Inflammation of the mouth)
Vomiting
Weight loss

How to use Lortinib Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lortinib 100mg Tablet is to be taken empty stomach.

How Lortinib Tablet works

Lortinib 100mg Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Lortinib 100mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Lortinib 100mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Lortinib 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Lortinib 100mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Lortinib 100mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Lortinib 100mg Tablet is recommended.
Use of this medicine is not advised in patients with severe kidney disease.

Liver

CAUTION

Lortinib 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Lortinib 100mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Lortinib 100mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Lortinib 100mg Tablet

₹790.0/Tablet

Erlonat 100mg Tablet

Natco Pharma Ltd

₹333/tablet

58% cheaper

Zyceva 100mg Tablet

Zydus Cadila

₹104.83/tablet

87% cheaper

Erleva 100mg Tablet

Glenmark Pharmaceuticals Ltd

₹117.5/tablet

85% cheaper

Erlotec 100mg Tablet

United Biotech Pvt Ltd

₹650/tablet

18% cheaper

Tyrokinin 100mg Tablet

Dr Reddy's Laboratories Ltd

₹633/tablet

20% cheaper

View all substitutes

Quick tips

Lortinib 100mg Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
It should be taken 1 hour before or 2 hours after the meal.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective clothing while going out.
It is advisable to avoid smoking while taking this medicine, as it makes the drug ineffective and requires dose adjustment.
Do not take it with medication lowering the stomach acid (such as antacids, H2 blockers including ranitidine), as it may affect the working of medicine.
Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Quinazoline Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

FAQs

How should Lortinib 100mg Tablet be taken?

Lortinib 100mg Tablet is a pill to be taken by mouth, once a day without food as prescribed by your doctor. It is important that you take Lortinib 100mg Tablet empty stomach, at least 1 hour before or 2 house after meals. It is advisable to take it the same time each day so that you remember when to take it.

Is Lortinib 100mg Tablet a chemotherapy drug?

Lortinib 100mg Tablet is not a conventional chemotherapy medicine. Lortinib 100mg Tablet belongs to a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This in turn helps to slow or stop the spread of cancer cells.

How long can I take Lortinib 100mg Tablet?

You need to take Lortinib 100mg Tablet every day, as long as your doctor prescribes it for you. The duration of treatment may vary from person to person.

Does smoking interfere with Lortinib 100mg Tablet?

Yes, smoking can interfere with the working of Lortinib 100mg Tablet. It can decrease the effectiveness of the medicine to a great extent. Hence, it is advised to stop smoking before you start Lortinib 100mg Tablet. Your doctor will need to adjust the dose of Lortinib 100mg Tablet, if you keep on smoking or there is a change in the pattern of smoking.

What should I do if I get a rash while taking Lortinib 100mg Tablet?

Rash is a common side effect of Lortinib 100mg Tablet but you should not stop taking Lortinib 100mg Tablet because of this. Consult your doctor who will suggest a treatment for it. Also, avoid sun-exposure, use a sunscreen and wear protective clothing.

When can I plan pregnancy, if I am taking Lortinib 100mg Tablet?

Avoid pregnancy while being treated with Lortinib 100mg Tablet. If you are a woman of child-bearing age use effective contraception during treatment. Avoid pregnancy for at least 1 month after taking the last tablet.

Does Lortinib 100mg Tablet affect eyes?

Lortinib 100mg Tablet commonly causes conjunctivitis and dry eyes. If you develop acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light, immediately inform the doctor as you may need urgent treatment.

When should I call my doctor during treatment with Lortinib 100mg Tablet?

Inform the doctor if you experience sudden difficulty in breathing associated with cough or fever, severe or ongoing diarrhea, loss of appetite, nausea, and vomiting. Also, consult your doctor if you experience acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light. Let your doctor know in case you are taking a statin (medicine to control cholesterol) along with this medicine and experience unexplained muscle pain, tenderness, weakness, or cramps.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1735-36.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 489-90.
Erlotinib. Seymour, Indiana: Schwarz Pharma Manufacturing; 2014 [revised May 2010]. [Accessed 23 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Erlotinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

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Address: 463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA

Country of origin: India

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