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Written By
Dr. Betina Chandolia
MDS, BDS
Reviewed By
Dr. Varun Gupta
MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Mesacol 500mg Suppository

Prescription Required
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Product introduction

Mesacol 500mg Suppository is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It is used when the lining tissue of the inner rectum becomes inflamed (proctitis). It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel.

Mesacol 500mg Suppository is used for the treatment of diseases caused by redness and swelling of lining of parts of intestines

Uses of Mesacol Suppository

Benefits of Mesacol Suppository

In Treatment of Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea, and abdominal pain. Mesacol 500mg Suppository can relieve these symptoms and also help you to stay well by preventing them from coming back. It is taken by the back passage (rectal route) and should not be taken orally. You need to use this medicine regularly to get the most out of it and you should drink plenty of fluids to make sure you stay hydrated.

Side effects of Mesacol Suppository

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mesacol

  • Rectal discomfort
  • Flatulence
  • Headache
  • Vomiting
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Rash

How to use Mesacol Suppository

Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.

How Mesacol Suppository works

Mesacol 500mg Suppository is an aminosalicylate. It works directly on the site of inflammation (swelling) in the lower parts of large intestine (colon and rectum) to provide rapid relief from attacks of ulcerative colitis. It suppresses the production of chemical messengers (prostaglandins) that cause intestinal inflammation, thereby reducing ulceration, bleeding and painful symptoms.

Safety advice

Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Mesacol 500mg Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Mesacol 500mg Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If you are taking Mesacol 500mg Suppository, monitor the baby for diarrhea.
Driving
No interaction found/established
Kidney
CAUTION
Mesacol 500mg Suppository should be used with caution in patients with kidney disease. Dose adjustment of Mesacol 500mg Suppository may be needed. Please consult your doctor.
Use of Mesacol 500mg Suppository is not recommended in patients with severe kidney disease.
Liver
CAUTION
Mesacol 500mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Mesacol 500mg Suppository may be needed. Please consult your doctor.

What if you forget to take Mesacol Suppository?

If you miss a dose of Mesacol 500mg Suppository, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Mesacol 500mg Suppository
₹23.54/Suppository
Meslataj Suppository
Taj Pharma India Ltd
₹17/suppository
22% cheaper

Quick tips

  • You have been prescribed Mesacol 500mg Suppository for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
  • It is for administration into the back passage (rectum). It must not be taken by mouth.
  • Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
  • Do not use Mesacol 500mg Suppository if you are allergic to aspirin or if you have blood disorders.
  • Do not stop using the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Aminosalicylic Acids Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
5- Aminosalicylic acid (5-ASA)

Patient concerns

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Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest.
Dr. Kunal Parasar
Surgical Gastroenterology
Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist
MORE
How long Tab Mesacol 400mg can be taken. I am consumed last 7 months.two time in aday
Dr. Anshul Varshney
Physician
Hello, Welcome to 1mg. I am Anshul Varshney for your help. You may need to consume it for at least 1 year if taking for ulcertaive colitis. A lot people need to take it for life long.
MORE
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FAQs

My symptoms have improved can I stop using Mesacol 500mg Suppository?

Continue to use Mesacol 500mg Suppository as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop using Mesacol 500mg Suppository without consulting your doctor.

I am suffering from ulcerative colitis (UC) and piles can I use Mesacol 500mg Suppository?

Mesacol 500mg Suppository is used for the treatment of ulcerative colitis, however, you should not start using the medicine on your own. Consult a doctor who will prescribe you the right dose and duration of treatment and will address any related or other concerns that you have.

Can I drink alcohol while using Mesacol 500mg Suppository?

You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Mesacol 500mg Suppository, you should consult your doctor before using alcohol.

When is the best time to use Mesacol 500mg Suppository?

Use Mesacol 500mg Suppository exactly as directed by your doctor. If you are using Mesacol 500mg Suppository suppositories you should insert it rectally, once daily at bedtime.
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    Disclaimer:

    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 867-69.
    2. MedlinePlus. Mesalazine/Mesalamine. [Accessed 28 Mar. 2019] (online) Available from:External Link
    3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mesalamine. [Updated 2019 Apr 1]. [Accessed 20 Feb. 2020] (online) Available from:External Link
    4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
    5. Mesalazine [Product Information]. Pymble, NSW: Ferring Pharmaceuticals Pty Ltd.; 2023. [Accessed 11 Jul. 2023]. (online) Available from:External Link
    6. Mesalazine [New Zealand Data Sheet]. Mt Wellington, Auckland: Pharmaco (NZ) Ltd.; 2023. [Accessed 11 Jul. 2023]. (online) Available from:External Link

    Marketer details

    Name: Sun Pharmaceutical Industries Ltd
    Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
    Country of origin: India

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