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Metagil-GM 1 Tablet SR


Product introduction

Metagil-GM 1 Tablet SR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Metagil-GM 1 Tablet SR is used in the treatment of type 2 diabetes mellitus . It is a combination medicine that can control blood sugar better than single medication. It should be used along with a proper diet and regular exercise for best results. Hypoglycemia (low blood sugar level) may occur as a side effect and it should be taken with food to avoid upset stomach.

Uses of Metagil-GM Tablet SR

Benefits of Metagil-GM Tablet SR

In Treatment of Type 2 diabetes mellitus

Metagil-GM 1 Tablet SR is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Metagil-GM Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metagil-GM

  • Hypoglycemia (low blood glucose level)
  • Headache
  • Nausea
  • Diarrhea
  • Flatulence

How to use Metagil-GM Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metagil-GM 1 Tablet SR is to be taken with food.

How Metagil-GM Tablet SR works

Metagil-GM 1 Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin.Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Metagil-GM 1 Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
Metagil-GM 1 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
UNSAFE
Metagil-GM 1 Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Metagil-GM 1 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Metagil-GM 1 Tablet SR may be needed. Please consult your doctor.
Use of Metagil-GM 1 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Metagil-GM 1 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Metagil-GM 1 Tablet SR may be needed. Please consult your doctor.
Metagil-GM 1 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you forget to take Metagil-GM Tablet SR?

If you miss a dose of Metagil-GM 1 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Metagil-GM 1 Tablet SR
₹3.4/Tablet SR
Prichek-M 1 Tablet SR
Indoco Remedies Ltd
₹8.9/tablet sr
162% costlier
Glimfirst-M 1 Tablet SR
Sinsan Pharmaceuticals
₹7.43/tablet sr
119% costlier
Metafort-G1 CP Tablet SR
Eris Lifesciences Ltd
₹7.11/tablet sr
109% costlier
Glimicure M 1 Tablet SR
HBC Lifesciences Pvt Ltd
₹5.9/tablet sr
74% costlier
₹4/tablet sr
18% costlier

Quick tips

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Metagil-GM 1 Tablet SR.
  • Take it with food to lower your chance of having an upset stomach.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Metagil-GM 1 Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

Patient concerns

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My father is taking trajenta 5 mg and gluconorn sr 1 gm but i think gluconorn sr 1 gm reduces appetite.
Dr. Rajesh Chhabra
Diabetology
Consult your doctor who recommended it.
I have so much pain in my head for last 8 years I consult so many but not getting relief ,I am very restless,full of anxiety my brain nerves become so hard please. Please write a medicine
Dr. Aanchal Maheshwari
Ayurveda
mix 100 gm brahmi , 100 gm jatamansi ,50 gm mulethi, 20 gm giloy say10 gm godanti bhasm, 5 gm praval bhasm . 5take above powder 1 spoon twice, Tablet sirah sooll adi vsvati with pathyadi kwath. Tablet cephagrain 2 tablet twice. Pour 1-2 drops of almomd oil in each of your nostril
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FAQs

What are the recommended storage conditions for Metagil-GM 1 Tablet SR?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of Metagil-GM 1 Tablet SR lead to lactic acidosis?

Yes, the use of Metagil-GM 1 Tablet SR can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Metagil-GM 1 Tablet SR and consult your doctor immediately.

What is Metagil-GM 1 Tablet SR?

Metagil-GM 1 Tablet SR is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

What are the possible side effects of Metagil-GM 1 Tablet SR?

The use of Metagil-GM 1 Tablet SR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Can the use of Metagil-GM 1 Tablet SR lead to Vitamin B12 deficiency?

Yes, the use of Metagil-GM 1 Tablet SR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Can the use of Metagil-GM 1 Tablet SR cause hypoglycemia?

Yes, the use of Metagil-GM 1 Tablet SR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.

Is it safe to take alcohol while I am also taking Metagil-GM 1 Tablet SR?

No, it is not safe to take Metagil-GM 1 Tablet SR along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110. [Accessed 28 Oct. 2021] (online) Available from:External Link

Marketer details

Name: Precise Lifescience
Address: No. 25, Nayandanahalli South Layout, Mysore Road, Bangalore - 560039
Country of origin: India

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