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Nigrain TR 40 Tablet SR
Prescription Required
Product introduction
Nigrain TR 40 Tablet SR helps decrease anxiety and relieve tremors. It is also used to help prevent migraine, heart-related chest pain (angina), and bleeding in the stomach caused by high blood pressure in the liver (portal hypertension).
Nigrain TR 40 Tablet SR may also be used to treat high blood pressure and some types of abnormal heartbeat (arrhythmia). The dose will depend on what you are being treated for and how you respond to the medicine. You should always take it as prescribed by the doctor. It should be taken on an empty stomach and at about the same time each day. You should keep taking it even if you feel well, as you are still getting the benefits. If you stop taking it suddenly, your condition may worsen.
The most common side effects are tiredness, weakness cold fingers and toes (Raynaud phenomenon), irregular or slow heartbeat, numbness in your fingers, and breathlessness. You may also experience nausea, vomiting, and diarrhea. Talk to your doctor if the side effects bother you or do not go away. Most side effects are short-lived and improve as your body gets used to the medicine.
You should not use this medicine if you have asthma, very slow or uneven heartbeats, or a serious heart condition, including heart failure. Talk to your doctor before taking it if you have kidney or liver problems or chronic obstructive pulmonary disease (COPD). In terms of lifestyle, alcohol may affect the way this medicine works and should be avoided. You should not drive if this medicine makes you feel dizzy. Ask your doctor whether it is safe to take this medicine if you are pregnant or breastfeeding.
Uses of Nigrain Tablet SR
- Prevention of Angina (heart-related chest pain)
- Treatment of Arrhythmia
- Prevention of Heart attack
- Treatment of Hypertension (high blood pressure)
- Treatment of Anxiety
- Treatment of Tremors
- Prevention of migraine
- Treatment of Pheochromocytoma
Benefits of Nigrain Tablet SR
In Prevention of Angina (heart-related chest pain)
Nigrain TR 40 Tablet SR relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.
In Treatment of Arrhythmia
Nigrain TR 40 Tablet SR is used to stabilize heart rate. It helps in normalizing an abnormal heart rhythm, preventing it occurring in the first place or slowing down the heart rate during an episode.
In Prevention of Heart attack
Nigrain TR 40 Tablet SR helps lower your blood pressure and make it easier for your heart to pump blood around your body. This reduces the chances of you having a heart attack. It can also reduce the risk of dying if it is given immediately after a heart attack. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.
In Treatment of Hypertension (high blood pressure)
Nigrain TR 40 Tablet SR relaxes the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.
In Treatment of Anxiety
Nigrain TR 40 Tablet SR stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. Nigrain TR 40 Tablet SR will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
In Treatment of Tremors
Nigrain TR 40 Tablet SR helps improve the flow of blood and prevents abnormal activity of muscles that trigger tremors. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.
In Prevention of migraine
Nigrain TR 40 Tablet SR helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency of migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.
In Treatment of Pheochromocytoma
While carrying out surgery for the removal of pheochromocytoma, there is a risk of abnormally high blood pressure. Nigrain TR 40 Tablet SR blocks the effect of some chemicals on your heart and blood vessels. This slows down the heart rate and helps the heartbeat with less force thereby lowering your blood pressure. It is used for the immediate reduction of very high blood pressure (hypertensive emergency). Controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.
Side effects of Nigrain Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nigrain
- Cold extremities
- Sleep disturbance
- Fatigue
- Slow heart rate
- Nightmares
How to use Nigrain Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nigrain TR 40 Tablet SR is to be taken empty stomach.
Avoid Nigrain TR 40 Tablet SR with high-fat meals such as olive oil, nuts & seeds (Brazil nuts), dark chocolate, butter and meat.
Avoid Nigrain TR 40 Tablet SR with high-fat meals such as olive oil, nuts & seeds (Brazil nuts), dark chocolate, butter and meat.
How Nigrain Tablet SR works
Nigrain TR 40 Tablet SR contains Propranolol, a beta blocker. It works by affecting the body’s response to nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for the heart to pump blood around the body. This prevents arrhythmias. It also widens the blood vessels in the body for better blood flow, thereby preventing angina as well as migraine. The exact mechanism by which it prevents tremors is not known, but experts believe that Nigrain TR 40 Tablet SR helps block the nerve impulses to the muscles responsible for tremors. Propranolol helps block the effects of the chemical messengers namely, adrenaline and noradrenaline, that are produced by the brain and are responsible for increasing your heart rate which makes you feel anxious. This way it helps with anxiety. While treating pheochromocytoma, Nigrain TR 40 Tablet SR may be given to block the action of high-adrenaline hormones, to lower the risk of developing dangerously high blood pressure during surgery for removing the tumor.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Nigrain TR 40 Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
Nigrain TR 40 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Nigrain TR 40 Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Nigrain TR 40 Tablet SR should be used with caution in patients with severe kidney disease. Dose adjustment of Nigrain TR 40 Tablet SR may be needed. Please consult your doctor.
Liver
CAUTION
Nigrain TR 40 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Nigrain TR 40 Tablet SR may be needed. Please consult your doctor.
What if you forget to take Nigrain Tablet SR?
If you miss a dose of Nigrain TR 40 Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- It is not the first-choice treatment for high blood pressure according to the latest guidelines.
- It may hide the symptoms of low blood sugar if you have diabetes. Monitor blood sugar levels regularly.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Use caution while driving or doing anything that requires concentration as Nigrain TR 40 Tablet SR can cause dizziness and sleepiness.
- Inform your doctor if you notice increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as these may be symptoms of heart failure.
- Do not stop taking the medication suddenly without talking to your doctor.
- It is not the first-choice treatment for high blood pressure according to the latest guidelines.
- It may hide the symptoms of low blood sugar if you have diabetes. Monitor blood sugar levels regularly.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Use caution while driving or doing anything that requires concentration as Nigrain TR 40 Tablet SR can cause dizziness and sleepiness.
- Inform your doctor if you notice increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as these may be symptoms of heart failure.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Chemical Class
Naphthalenes derivatives
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Beta blocker- Non selective
Patient concerns
User feedback
Patients taking Nigrain TR 40 Tablet SR
Once A Day
79%
Twice A Day
19%
Alternate Day
1%
Thrice A Day
1%
What are you using Nigrain Tablet SR for?
High blood pr*
40%
Chest pain (A*
20%
Anxiety
20%
Arrhythmias
20%
*High blood pressure, Chest pain (Angina)
How much was the improvement?
Excellent
100%
FAQs
My doctor has prescribed Nigrain TR 40 Tablet SR even though my blood pressure is within normal limits. Is it because of the chest pain that I complained of?
Yes, it is possible that your doctor prescribed Nigrain TR 40 Tablet SR for chest pain (angina). Nigrain TR 40 Tablet SR is a beta-blocker that is used to lower high blood pressure, prevent angina, treat or prevent heart attacks or reduce your risk of heart problems following a heart attack. Nigrain TR 40 Tablet SR is also used to treat irregularities in the heartbeat, including those caused by anxiety, essential tremor (shaking of the head, chin and hands). It also prevents migraine headaches, overactive thyroid (thyrotoxicosis and hyperthyroidism), and bleeding in the food pipe caused by high blood pressure.
When can I expect relief in my symptoms after starting Nigrain TR 40 Tablet SR for high blood pressure?
Nigrain TR 40 Tablet SR usually starts working within a few hours of taking it. However, it may take up to a week to see the full benefits of the symptoms of high blood pressure or heart conditions. You may not notice any difference, but that does not mean it is not working. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Can Nigrain TR 40 Tablet SR be used in asthmatics?
No, Nigrain TR 40 Tablet SR cannot be used in asthmatics. This is because using Nigrain TR 40 Tablet SR in asthma patients can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any episodes of difficulty breathing, before starting treatment with Nigrain TR 40 Tablet SR.
What if I forget to take a dose of Nigrain TR 40 Tablet SR?
If you forget a dose of Nigrain TR 40 Tablet SR, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Can I stop taking Nigrain TR 40 Tablet SR as my chest pain is under control?
No, you should not stop taking Nigrain TR 40 Tablet SR suddenly because that may worsen your angina or may cause a heart attack. Tell your doctor and if there is a need to stop Nigrain TR 40 Tablet SR, your doctor will reduce your dose gradually over a period of a few weeks.
Does Nigrain TR 40 Tablet SR relieve anxiety?
Yes, Nigrain TR 40 Tablet SR helps relieve the symptoms of anxiety such as irritability, restlessness, excessive worry, lack of concentration, racing or unwanted thoughts, fatigue, insomnia (lack of sleep), palpitations (irregular heart rate), or trembling. The dose and duration of taking Nigrain TR 40 Tablet SR will be suggested by your doctor, depending on whether your symptoms are a recurring problem or occur only in stressful conditions. However, Nigrain TR 40 Tablet SR is usually given for the short-term treatment of anxiety. If you have any doubts, consult your doctor.
What other lifestyle changes should I make while taking Nigrain TR 40 Tablet SR?
Lifestyle changes play a major role in keeping you healthy if you are taking Nigrain TR 40 Tablet SR. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables, and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Nigrain TR 40 Tablet SR and to keep yourself healthy.
Is Nigrain TR 40 Tablet SR effective?
Nigrain TR 40 Tablet SR is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Nigrain TR 40 Tablet SR too early, the symptoms may return or worsen.
What if I take an overdose of Nigrain TR 40 Tablet SR?
If you take an overdose of Nigrain TR 40 Tablet SR you may experience symptoms such as slow heartbeat, trembling, difficulty breathing, or dizziness. However, the response of taking too much of Nigrain TR 40 Tablet SR varies from person to person. It would be best to consult a doctor if you think you have taken more than what you are prescribed.
Is Nigrain TR 40 Tablet SR safe?
Nigrain TR 40 Tablet SR is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
I have been on Indomethacin for several months. Will it be a problem if I start taking Nigrain TR 40 Tablet SR along with it?
Yes, Indomethacin may interfere with the working of Nigrain TR 40 Tablet SR and make it less effective. As a result, your blood pressure may increase. Speak to your doctor who will prescribe you a different medicine to control blood pressure.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 320.
- Opie LH. β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 28-29.
- Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 175-76.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1162-63.
- Drugs.com. Propranolol Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Marketer details
Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Country of origin: India
Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Nigrain TR 40 Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Nigrain TR 40 Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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