Pazolit 400mg Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.

Pazolit 400mg Tablet is used to treat different types of cancer

Uses of Pazolit Tablet

Benefits of Pazolit Tablet

In Kidney cancer

Pazolit 400mg Tablet is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Soft tissue sarcoma

Soft tissue sarcoma is a type of sarcoma that develops in tissues such as bone and muscles. Pazolit 400mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.

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Side effects of Pazolit Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pazolit

Headache
Nausea
Vomiting
Musculoskeletal (bone, muscle or joint) pain
Fatigue
Change in color of hair
Diarrhea
High blood pressure
Decreased appetite
Weight loss
Taste change
Abnormal skin pigmentation
Hair discoloration
Tumor pain
Breathlessness

How to use Pazolit Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pazolit 400mg Tablet is to be taken empty stomach.

How Pazolit Tablet works

Pazolit 400mg Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (tyrosine kinase) that are responsible for the proliferation of the cancerous cells. It also restricts the growth of new blood vessels within the tumor. This is how it works against cancer.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pazolit 400mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Pazolit 400mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Pazolit 400mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Pazolit 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Pazolit 400mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Pazolit 400mg Tablet is recommended.

Liver

CAUTION

Pazolit 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pazolit 400mg Tablet may be needed. Please consult your doctor.
Use of Pazolit 400mg Tablet is not advised in patients with moderate to severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pazolit 400mg Tablet

₹73.33/Tablet

Votrient 400mg Tablet

Glaxo SmithKline Pharmaceuticals Ltd

₹579/tablet

690% costlier

Pazoci 400 Tablet

Cipla Ltd

₹333.17/tablet

354% costlier

Pazolee 400mg Tablet

Admac Pharma Ltd

₹530/tablet

623% costlier

Pazroto 400mg Tablet

Abbott

₹350/tablet

377% costlier

Pazobrite 400mg Tablet

Torrent Pharmaceuticals Ltd

₹347.4/tablet

374% costlier

View all substitutes

Fact Box

Chemical Class

Alkyldiarylamines Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

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FAQs

Is Pazolit 400mg Tablet a chemotherapy medicine?

Pazolit 400mg Tablet is not a conventional chemotherapy medicine. It belongs to a class of medicine called a protein kinase inhibitor. Pazolit 400mg Tablet works by preventing the activity of proteins that are involved in the growth and spread of cancer cells.

How should I take Pazolit 400mg Tablet?

Pazolit 400mg Tablet should be taken orally by mouth once a day or as directed by your doctor. Swallow the tablets whole with water, do not break or crush the tablets. This affects the way the medicine is absorbed and may increase the chance of side effects.

Can Pazolit 400mg Tablet be taken with food?

Pazolit 400mg Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after food. If it is taken with food, the dosage may need to be increased. Doing this will in turn cause more side effects.

How will I know if Pazolit 400mg Tablet is helping me?

The duration for which you have to continue taking Pazolit 400mg Tablet varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Are there any food restrictions while I’m taking Pazolit 400mg Tablet?

Yes, it is best to avoid grapefruit and grapefruit juice while on Pazolit 400mg Tablet, as it may affect how the medicine works in your body. Ask your doctor about any additional foods you should avoid.

How long I have to take Pazolit 400mg Tablet?

What is the most important information I need to know about Pazolit 400mg Tablet?

Pazolit 400mg Tablet may cause severe or life-threatening liver damage. Inform your doctor if you have or had liver disease. If you experience any of the following symptoms such as discoloration of the skin or eyes (yellowing), dark urine, extreme tiredness, nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, or unusual bleeding or bruising, call your doctor immediately. Your doctor may ask you to take some lab tests before you start taking Votrient. After you start taking Votrient, you may need to take those lab tests at weeks 3, 5, 7 and 9 and then at months 3 and 4. Your doctor may also prescribe additional tests if necessary. Periodic testing should then continue after 4 months.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1072-73.
Pazopanib. Research Triangle Park, North Carolina: GlaxoSmithKline; 2009 [revised Apr. 2012]. [Accessed 24 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Marketer details

Name: Sun Pharmaceutical Industries Ltd

Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.