Pemgli 1 Tablet belongs to a group of medicines called sulfonylureas and is used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes thereby preventing serious complications of diabetes such as kidney damage and blindness.

Pemgli 1 Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It helps to control blood sugar levels and thus prevent the long-term complications of diabetes. Use this medicine along with a proper diet and exercise for best results. It may cause hypoglycemia (low blood sugar level) as a side effect. Monitor your blood sugar level regularly while you are taking this medicine.

Uses of Pemgli Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Pemgli Tablet

In Treatment of Type 2 diabetes mellitus

Pemgli 1 Tablet increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking Pemgli 1 Tablet regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Pemgli Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pemgli

Hypoglycemia (low blood glucose level)
Headache
Nausea
Dizziness
Weakness

How to use Pemgli Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pemgli 1 Tablet is to be taken with food.

How Pemgli Tablet works

Pemgli 1 Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Pemgli 1 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Pemgli 1 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Pemgli 1 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Pemgli 1 Tablet

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Pemgli 1 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pemgli 1 Tablet may be needed. Please consult your doctor.
Use of Pemgli 1 Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.

Liver

CAUTION

Pemgli 1 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pemgli 1 Tablet may be needed. Please consult your doctor.
However, the use of Pemgli 1 Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.

What if you forget to take Pemgli Tablet?

If you missed a a dose of Pemgli 1 Tablet, skip the missed dose and take your next dose at the usual time.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pemgli 1 Tablet

₹3.2/Tablet

Amaryl 1mg Tablet

Sanofi India Ltd

₹4.14/tablet

29% costlier

GP 1 Tablet

USV Ltd

₹4.14/tablet

29% costlier

Zoryl 1 Tablet

Intas Pharmaceuticals Ltd

₹4.14/tablet

29% costlier

Glimestar 1 Tablet

Mankind Pharma Ltd

₹2.99/tablet

7% cheaper

Azulix 1 Tablet

Torrent Pharmaceuticals Ltd

₹3.7/tablet

16% costlier

View all substitutes

Quick tips

Take Pemgli 1 Tablet shortly before or with the first main meal of the day (usually breakfast).
Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
Monitor your blood sugar level regularly while you are taking Pemgli 1 Tablet.
Pemgli 1 Tablet can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Be careful while driving or operating machinery until you know how Pemgli 1 Tablet affects you.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Chemical Class

Third-generation Sulfonylurea Derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Sulfonylureas (Insulin Secretogogues)

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

What is the dosage of Pemgli 1 Tablet?

The recommended starting dose of Pemgli 1 Tablet is 1 mg or 2 mg once daily, administered with breakfast. If you are at a higher risk of low blood sugar (e.g., the elderly or patients with renal impairment), you will be given a starting dose of 1 mg once daily. The usual maintenance dose is 1–4 mg once daily. The maximum recommended dose is 8 mg once daily. After reaching a daily dose of 2 mg, the dosage will be increased not more than 2 mg at 1- to 2-week intervals, based on your blood glucose level.

Does Pemgli 1 Tablet make you sleepy?

Pemgli 1 Tablet itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.

Is Pemgli 1 Tablet safe for kidneys?

Pemgli 1 Tablet does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Pemgli 1 Tablet is principally eliminated by the kidneys.

Does Pemgli 1 Tablet cause memory loss?

No, it is not known that Pemgli 1 Tablet causes memory loss. However, the use of Pemgli 1 Tablet may cause low blood sugar which may cause problems with concentration and reduced alertness.

Who should not take Pemgli 1 Tablet?

Pemgli 1 Tablet should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Pemgli 1 Tablet.

How long does it take for Pemgli 1 Tablet to start working?

Pemgli 1 Tablet takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.

How long do I need to take Pemgli 1 Tablet? Can I stop the medication?

Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Pemgli 1 Tablet only controls the sugar levels but does not cure it. Do not stop taking Pemgli 1 Tablet without talking to your doctor. If you stop taking Pemgli 1 Tablet suddenly your diabetes may get worse.

What can happen if I take more than the recommended dose of Pemgli 1 Tablet?

Pemgli 1 Tablet should be taken strictly as advised by the doctor. Overdose of Pemgli 1 Tablet may significantly decrease your blood sugar levels (hypoglycemia). If you think you have taken an excess dose and experience a dip in your sugar level, consume enough sugar (e.g., a small bar of sugar cubes, sweet juice or sweetened tea) and inform a doctor immediately. Severe cases of hypoglycemia accompanied by loss of consciousness and coma require immediate medical treatment and admission into hospital.

Can you take Pemgli 1 Tablet on an empty stomach?

No. Taking Pemgli 1 Tablet on an empty stomach can cause your blood sugar levels to become too low. Low blood sugar can cause dizziness, shaking, anxiety, irritability, a fast heartbeat, and confusion. Therefore, you should always take the medicine with breakfast or the first meal of the day. If you are skipping your meal, then you should also avoid taking Pemgli 1 Tablet.

Can Pemgli 1 Tablet cause weight gain?

Yes, Pemgli 1 Tablet can cause weight gain. Pemgli 1 Tablet is a sulfonylurea drug and causes the pancreas to release insulin. It may stimulate hunger and cause mild weight gain in some people. Patients are advised to eat a healthy balanced diet and exercise regularly to keep their weight stable.

Can Pemgli 1 Tablet cause dizziness?

Yes, Pemgli 1 Tablet can cause dizziness as a side effect. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while travelling.

What should you not eat while taking Pemgli 1 Tablet?

It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar.

Is Pemgli 1 Tablet safe to use?

Yes, Pemgli 1 Tablet tablet is safe when used as directed by the doctor. However, it may show some side effects. For best results, it should be used in the correct dose and at the same time each day.

Can people with diabetes have proteins?

Yes, people with diabetes must include proteins along with other essential nutrients in their daily diet. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet.

Are artificial sweeteners good for people with diabetes?

No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.

Can diabetes cause kidney failure?

Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.

Can diabetes be cured?

Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

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Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 740.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 629-30.
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