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Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:15 PM (IST)

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Pyrostig 60mg Tablet

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Product introduction

Pyrostig 60mg Tablet is used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), and postoperative urinary retention. It helps strengthen the muscles, promotes bowel function, and stimulates the bladder muscles.

Pyrostig 60mg Tablet improves nerve activity.

Uses of Pyrostig Tablet

Benefits of Pyrostig Tablet

In Treatment of Myasthenia gravis

Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Pyrostig 60mg Tablet makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.

In Treatment of Paralytic ileus

Paralytic ileus is the obstruction of the intestines due to improper functioning of the nerves and muscles in the intestine that impairs digestive movement. Pyrostig 60mg Tablet induces contractions in the intestinal muscles and improves their function. As a result, there is better movement of food and this treats the obstruction. Take it as advised by the doctor and follow your doctor’s instructions carefully.

In Treatment of Post-operative urinary retention

After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Pyrostig 60mg Tablet helps to improve this problem and treats post-operative urinary retention effectively.

Side effects of Pyrostig Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pyrostig

  • Nausea
  • Excessive salivation
  • Diarrhea
  • Blurred vision
  • Breathlessness
  • Watery eyes
  • Abdominal pain
  • Altered frequency of urination
  • Sweating
  • Headache
  • Dizziness
  • Runny nose
  • Heartburn
  • Gastro-esophageal reflux disease
  • Paresthesia (tingling or pricking sensation)
  • Muscle twitching
  • Weakness
  • Muscle cramp
  • Increased bronchial secretions

How to use Pyrostig Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pyrostig 60mg Tablet is to be taken empty stomach.

How Pyrostig Tablet works

Pyrostig 60mg Tablet increases the levels of acetylcholine (chemical messenger) which allows free transmission of signals across the nerves and muscles.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pyrostig 60mg Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Pyrostig 60mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Pyrostig 60mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Pyrostig 60mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Pyrostig 60mg Tablet may reduce the sharpness of your eyesight and therefore your ability to drive or use machines. Do not drive or operate machines if this medicine affects your ability to see clearly.
Kidney
CAUTION
Pyrostig 60mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pyrostig 60mg Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Pyrostig 60mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Pyrostig Tablet?

If you miss a dose of Pyrostig 60mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pyrostig 60mg Tablet
₹15.9/Tablet
Distinon Tablet
Samarth Life Sciences Pvt Ltd
₹11.21/tablet
29% cheaper
Gravitor Tablet
Sun Pharmaceutical Industries Ltd
₹8.24/tablet
48% cheaper
Myestin 60mg Tablet
Vhb Life Sciences Inc
₹16.6/tablet
4% costlier
Mustone 60mg Tablet
Chandra Bhagat Pharma Pvt Ltd
₹7.99/tablet
50% cheaper
Mygris 60mg Tablet
Bharat Serums & Vaccines Ltd
₹7.79/tablet
51% cheaper

Quick tips

  • You have been prescribed Pyrostig 60mg Tablet for treatment of myasthenia gravis.
  • It may also be used to treat inactivity of the muscle in the intestines (paralytic ileus) and difficulty in passing urine (urinary retention) after an operation.
  • Take it with food to avoid an upset stomach.
  • Take it as per the dose and duration advised by your doctor. Overdosing can result in extreme muscle weakness.
  • It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not drink alcohol while taking this medicine as it may worsen the side effects.
  • Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Fact Box

Chemical Class
N-Methylpyridinium Compounds
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Cholinesterase inhibitors- carbamates

Patient concerns

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FAQs

Does Pyrostig 60mg Tablet cure myasthenia gravis? For how long do I need to take it?

Pyrostig 60mg Tablet helps reduce and improve muscle weakness and hence relieves the symptoms of myasthenia gravis but does not cure it. The length of time for which you have to take Pyrostig 60mg Tablet will depend on your needs. You should not stop taking Pyrostig 60mg Tablet until and unless advised by your doctor, even if you start feeling better.

Will Pyrostig 60mg Tablet have any effect on my baby if I am breastfeeding?

A very small quantity of Pyrostig 60mg Tablet passes into breast milk, which may or may not affect your baby. Ask your doctor if you can continue to breastfeed your baby.

Can I take Pyrostig 60mg Tablet for constipation?

No, Pyrostig 60mg Tablet should not be taken for any type of constipation. It is used only when constipation occurs due to paralysis of the intestine and strictly on prescription by the doctor.

Who should not take Pyrostig 60mg Tablet?

Pyrostig 60mg Tablet should not be taken by patients who are allergic to it. It should also be avoided by patients who are constipated or cannot urinate, unless the doctor has advised to use this medicine. This is because Pyrostig 60mg Tablet is only used to treat certain types of constipation and inability to pass urine.

What should I do if I have accidentally taken more than the required dose?

You should immediately seek help at a nearby hospital or contact your doctor urgently. An excess dose of Pyrostig 60mg Tablet may cause stomach pain, nausea, vomiting, diarrhea, excessive sweating, salivation, blurred vision, excessive weakness, difficulty in breathing, and even paralysis.

Is Pyrostig 60mg Tablet a steroid?

No, Pyrostig 60mg Tablet is not a steroid. It belongs to anticholinesterases group of medicines. Pyrostig 60mg Tablet works by preventing the breakdown of a chemical called acetylcholine.

Does Pyrostig 60mg Tablet have any abuse potential?

No, there is no evidence that Pyrostig 60mg Tablet has abuse potential.

Does it cause weight gain?

No, Pyrostig 60mg Tablet does not cause weight gain. If you experience weight gain, it may be due to inactivity related to muscle weakness in myasthenia gravis.

Is Pyrostig 60mg Tablet safe to use?

Yes, Pyrostig 60mg Tablet is safe if used according to the doctor’s advice. You should not exceed the dose as prescribed by the doctor.

Is it safe to drive if I have taken Pyrostig 60mg Tablet?

Pyrostig 60mg Tablet may cause blurred vision, and therefore you should limit driving until you know how it affects you.
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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1172-73.
    2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pyridostigmine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:External Link
    3. Pyridostigmine. Hertfordshire, UK: Mylan Products Limited; 1998 [revised 27 Feb. 2018]. [Accessed 22 Mar. 2019] (online) Available from:External Link
    4. Pyridostigmine Bromide [New Zealand Consumer Medicine Information]. Auckland, New Zealand: iNova Pharmaceuticals (NZ) Limited; 2022. [Accessed 05 Aug 2023] (online) Available from:External Link
    5. Taj Life Sciences. Pyridostigmine bromide [Product Information]. [Accessed 05 Aug 2023] (online) Available from:External Link
    6. Pyridostigmine bromide [Prescribing Information]. Bridgewater, NJ: Bausch Health US, LLC.; 2020. [Accessed 05 Aug. 2023] (online) Available from:External Link

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    Address: BLOCK-F, TF-303, SUMEL-6, JUPITER MILL COMPOUND, DUDHESHWAR ROAD, DUDHESHWAR, Ahmedabad, Gujarat, 380004
    Country of origin: India

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