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Written By
Dr. Shreya Gupta
MDS (Oral Pathology & Microbiology), BDS
Reviewed By
Dr. Ashish Ranjan
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:15 PM (IST)

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Sevanier 400 Tablet

Prescription Required
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Product introduction

Sevanier 400 Tablet is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood.

Sevanier 400 Tablet is used to control the levels of phosphate in the blood of adult kidney failure patients on dialysis

Uses of Sevanier Tablet

Side effects of Sevanier Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sevanier

  • Nausea
  • Vomiting
  • Upper abdominal pain
  • Flatulence
  • Constipation
  • Diarrhea

How to use Sevanier Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sevanier 400 Tablet is to be taken with food.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sevanier 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sevanier 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Sevanier 400 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Sevanier 400 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Sevanier 400 Tablet is safe to use in patients with kidney disease. No dose adjustment of Sevanier 400 Tablet is recommended.
However, regular monitoring of calcium levels is advisable in these patients.
Liver
SAFE IF PRESCRIBED
Sevanier 400 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sevanier 400 Tablet may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Sevanier 400 Tablet
₹19.0/Tablet
Revlamer 400 Tablet
Sun Pharmaceutical Industries Ltd
₹4.28/tablet
77% cheaper
Sevcar 400 Tablet
Emcure Pharmaceuticals Ltd
₹35.71/tablet
88% costlier
Sevlaren 400 Tablet
La Renon Healthcare Pvt Ltd
₹23.5/tablet
24% costlier
Phoscut 400 Tablet
Steadfast Medishield Pvt Ltd
₹9.34/tablet
51% cheaper
Acutrol C 400 Tablet
Intas Pharmaceuticals Ltd
₹11.8/tablet
38% cheaper

Quick tips

  • Sevanier 400 Tablet is used to control blood phosphate level in patients that are on dialysis treatment.
  • You must take it with food and stick to the diet prescribed by your doctor.
  • You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
  • Avoid taking any other medicine 1 hour before or 3 hours after taking Sevanier 400 Tablet.
  • Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.
  • Sevanier 400 Tablet is used to control blood phosphate level in patients that are on dialysis treatment.
  • You must take it with food and stick to the diet prescribed by your doctor.
  • You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary.
  • Avoid taking any other medicine 1 hour before or 3 hours after taking Sevanier 400 Tablet.
  • Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery.

Fact Box

Chemical Class
Epoxide
Habit Forming
No
Therapeutic Class
OTHERS
Action Class
Phosphorous binder

Patient concerns

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Shikha Mishra
Dietetics/Nutrition
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Blood sugar levels high suggest me
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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FAQs

Is Sevanier 400 Tablet taken with food?

Yes, Sevanier 400 Tablet can be taken with food. It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sevanier 400 Tablet works by binding to phosphate from food. Take it exactly as advised by your doctor.

Can Sevanier 400 Tablet be crushed?

No, you should not crush, chew, or break Sevanier 400 Tablet into pieces. You should swallow it as a whole with water.

Why is it important for me to take Sevanier 400 Tablet?

It is important to take Sevanier 400 Tablet as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sevanier 400 Tablet, as it binds phosphate from food in the digestive tract.

Does Sevanier 400 Tablet cause constipation?

A common side effect of Sevanier 400 Tablet is constipation, though it does not occur in everyone. The other common side effects of the stomach and intestine include diarrhea, indigestion, flatulence, and pain in the abdomen. Immediately consult your doctor if these side effects become severe and disturb you.

Who should not take Sevanier 400 Tablet?

Patients who are allergic to Sevanier 400 Tablet and who have low levels of phosphate in blood should avoid taking Sevanier 400 Tablet. Additionally, patients having intestinal obstruction should also avoid using Sevanier 400 Tablet.

Can I take ciprofloxacin while I am taking Sevanier 400 Tablet?

Ciprofloxacin may interfere with the working of Sevanier 400 Tablet and therefore it should not be taken at the same time as Sevanier 400 Tablet. However, if taken together then a gap of at least 2 hours before or 6 hours after taking Sevanier 400 Tablet should be maintained.

How long do I need to take Sevanier 400 Tablet?

Continue taking Sevanier 400 Tablet as long as recommended by your doctor. Sevanier 400 Tablet lowers your dietary phosphate levels but does not cure your disease. Hence, you may have to take it lifelong, as stopping Sevanier 400 Tablet may increase your phosphate levels.

Do I need to have any tests while taking Sevanier 400 Tablet?

Yes, serum phosphate levels should be monitored regularly while you are taking Sevanier 400 Tablet. Also, the use of Sevanier 400 Tablet may decrease the levels of vitamin D, A, E, K, and folic acid and hence the levels need to be monitored during the treatment.
Related lab tests
  • Calcium
  • Phosphorus, Serum
  • Phosphorus, Urine

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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1259.
    2. Medscape. Sevelamer. [Accessed 6 Apr. 2019] (online) Available from:External Link
    3. Sevelamer hydrochloride. Guildford, Surrey: SANOFI; 2000 [revised 20 Dec. 2018]. [Accessed 30 Jan. 2019] (online) Available from:External Link
    4. Sevelamer. Cambridge, USA: Genzyme Corporation; 1998. [Accessed 6 Apr. 2019] (online) Available from:External Link
    5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:External Link
    6. Sevelamer Carbonate [Product Information]. Ahmedabad, Gujarat: La Renon. [Accessed 06 Aug. 2023]. (online) Available from:External Link
    7. National Center for Biotechnology Information. PubChem Compound Summary for , Sevelamer. [Accessed 06 Aug. 2023]. (online) Available from:External Link

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    Address: Address- 102-103, 1st Floor, Vardhman Key Point Plaza, Sector 6, Dwarka, New Delhi
    Country of origin: India

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