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Home>Tibetrit>tibetrit 450mg/300mg/800mg combipack

TIBETRIT 450MG/300MG/800MG COMBIPACK

Prescription Required

Introduction of Tibetrit Tablet

TIBETRIT 450MG/300MG/800MG COMBIPACK is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

TIBETRIT 450MG/300MG/800MG COMBIPACK is a combination of rifampicin, isoniazid, and ethambutol.

Uses of Tibetrit Tablet

Benefits of Tibetrit Tablet

In Treatment of Tuberculosis (TB)

Tuberculosis is an infectious disease that mainly affects the lungs but can affect other parts of the body as well. TIBETRIT 450MG/300MG/800MG COMBIPACK helps treat tuberculosis by stopping the growth of bacteria causing infection. Your symptoms might improve after using TIBETRIT 450MG/300MG/800MG COMBIPACK. However, make sure to complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Tibetrit Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tibetrit

  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Watery eyes
  • Increased liver enzymes
  • Jaundice
  • Visual impairment
  • Increased uric acid level in blood
  • Gout
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Tibetrit Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. TIBETRIT 450MG/300MG/800MG COMBIPACK is to be taken empty stomach.
Avoid TIBETRIT 450MG/300MG/800MG COMBIPACK with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking TIBETRIT 450MG/300MG/800MG COMBIPACK may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
TIBETRIT 450MG/300MG/800MG COMBIPACK may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
TIBETRIT 450MG/300MG/800MG COMBIPACK is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
TIBETRIT 450MG/300MG/800MG COMBIPACK may cause side effects which could affect your ability to drive.
TIBETRIT 450MG/300MG/800MG COMBIPACK occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
TIBETRIT 450MG/300MG/800MG COMBIPACK should be used with caution in patients with kidney disease. Dose adjustment of TIBETRIT 450MG/300MG/800MG COMBIPACK may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
TIBETRIT 450MG/300MG/800MG COMBIPACK should be used with caution in patients with liver disease. Dose adjustment of TIBETRIT 450MG/300MG/800MG COMBIPACK may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
TIBETRIT 450MG/300MG/800MG COMBIPACK
₹4.67/Tablet
R-Cinex E Tablet
Lupin Ltd
₹18.5/tablet
295% costlier
Rhe-FD Tablet
Macleods Pharmaceuticals Pvt Ltd
₹18.48/tablet
295% costlier
Trac 3 450 mg/300 mg/800 mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹3.82/tablet
18% cheaper
Mycocox E 450 mg/300 mg/800 mg Tablet
Cadila Pharmaceuticals Ltd
₹8.91/tablet
90% costlier
Monto 3 Tablet
Shreya Life Sciences Pvt Ltd
₹10.01/tablet
114% costlier

Quick tips

Tibetrit Tablet

  • It is best to take the medicine on an empty stomach one hour before or two hours after meals.
  • Finish the prescribed course of medicine, even if you start to feel better. Stopping it early may make the infection harder to treat.
  • It can make birth control pills less effective so ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).
  • It can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. 

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

Patient concerns

arrow
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
MORE
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
MORE
arrow

FAQs

Tibetrit Tablet

Which is the best time to take TIBETRIT 450MG/300MG/800MG COMBIPACK?

Take TIBETRIT 450MG/300MG/800MG COMBIPACK exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Can the use of TIBETRIT 450MG/300MG/800MG COMBIPACK make birth control pills ineffective?

Yes, TIBETRIT 450MG/300MG/800MG COMBIPACK can make birth control pills less effective. Ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).

Is tuberculosis a curable disease?

Yes, tuberculosis (TB) is a curable disease and can be cured with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side effects.

What are the instructions for the storage and disposal of TIBETRIT 450MG/300MG/800MG COMBIPACK?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of TIBETRIT 450MG/300MG/800MG COMBIPACK cause discoloration of the urine?

Yes, TIBETRIT 450MG/300MG/800MG COMBIPACK contains rifampicin which can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Call your doctor if you have discoloration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).

Can I discontinue TIBETRIT 450MG/300MG/800MG COMBIPACK if I feel well?

No, do not discontinue TIBETRIT 450MG/300MG/800MG COMBIPACK. Take the proper course of the drug that has been prescribed to you even if you begin to feel better. If you stop taking TIBETRIT 450MG/300MG/800MG COMBIPACK, your infection may become worse and difficult to treat. It may even result in drug-resistant TB i.e. drugs you were taking may no longer work for Tuberculosis.

Can TIBETRIT 450MG/300MG/800MG COMBIPACK cause visual impairment?

TIBETRIT 450MG/300MG/800MG COMBIPACK contains Ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.
Related lab tests
  • Complete Blood Count
  • Erythrocyte Sedimentation Rate
  • Mycobacterium Tuberculosis DNA PCR - Qualitative
  • Peripheral Smear Examination

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    Disclaimer:

    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Hilal-Dandan R, Brunton LL. Goodman and Gilman's Manual of Pharmacology and Therapeutics. 2nd ed. New York, New York: The McGraw-Hill Companies, Inc.; 2014. [Accessed 10 Apr. 2019] (online) Available from:External Link
    2. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 10 Apr. 2019] (online) Available from:External Link
    3. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 10 Apr. 2019] (online) Available from:External Link

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