Tilistigmin 15mg Tablet is used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and reversal of effect of skeletal muscle relaxants after surgery.

Tilistigmin 15mg Tablet improves nerve activity.

Uses of Tilistigmin Tablet

Myasthenia gravis
Paralytic ileus
Post-operative urinary retention
Reversal of effect of skeletal muscle relaxant after surgery

Benefits of Tilistigmin Tablet

In Myasthenia gravis

Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Tilistigmin 15mg Tablet makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.

In Paralytic ileus

Paralytic ileus is the obstruction of the intestines due to improper functioning of the nerves and muscles in the intestine that impairs digestive movement. Tilistigmin 15mg Tablet induces contractions in the intestinal muscles and improves their function. As a result, there is better movement of food and this treats the obstruction. Take it as advised by the doctor and follow your doctor’s instructions carefully.

In Post-operative urinary retention

After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Tilistigmin 15mg Tablet helps to improve this problem and treats post-operative urinary retention effectively.

In Reversal of effect of skeletal muscle relaxant after surgery

Skeletal muscle relaxants are given to induce anesthesia and to carry out surgical or certain diagnostic procedures. This blocks the conduction of signals between nerves and muscles. After the surgery, Tilistigmin 15mg Tablet is given to reverse this effect and cause muscle contraction again to restore normal function.

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Side effects of Tilistigmin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tilistigmin

Nausea
Vomiting
Abdominal cramp
Diarrhea
Increased saliva production

How to use Tilistigmin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tilistigmin 15mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Tilistigmin Tablet works

Tilistigmin 15mg Tablet is a reversible cholinesterase inhibitor. When taken by mouth it increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.

Safety advice

Alcohol

UNSAFE

Tilistigmin 15mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Tilistigmin 15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Tilistigmin 15mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Tilistigmin 15mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Tilistigmin 15mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tilistigmin 15mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.

Liver

SAFE IF PRESCRIBED

Tilistigmin 15mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tilistigmin 15mg Tablet may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Tilistigmin 15mg Tablet

₹4.98/Tablet

Tilstigmin Tablet

Tablets India Limited

₹5.55/tablet

11% costlier

Quick tips

You have been prescribed Tilistigmin 15mg Tablet for treatment of myasthenia gravis.
It may also be used to treat inactivity of the muscle in the intestines (paralytic ileus) and difficulty in passing urine (urinary retention) after an operation.
Take it as per the dose and duration advised by your doctor. Overdosing can result in extreme muscle weakness.
Do not drink alcohol while taking this medicine as it may worsen the side effects.
Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Fact Box

Chemical Class

Phenoxy Compounds

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Cholinesterase inhibitors- carbamates

Patient concerns

Drooping of eyelids. What is the cause of it? What is the remedy?

Dr. Vishal Maniar

Ophthalmology

At ur age u need detailed eye checkup and neurologist referenceTo rule out myasthenia gravis, ocular palsy Bells palsy,diabetes,trauma

Right medicine for myasthenia gravis

Dr. Vikas Sharma

Neurology

many ; cant advise online as they are strong medicine

FAQs

Does Tilistigmin 15mg Tablet treat myasthenia gravis? How long do I need to take it?

Tilistigmin 15mg Tablet relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Tilistigmin 15mg Tablet will depend on your condition. Do not stop taking Tilistigmin 15mg Tablet until and unless advised by your doctor, even if you start feeling better.

How long does Tilistigmin 15mg Tablet take to start working?

Tilistigmin 15mg Tablet takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.

Is Tilistigmin 15mg Tablet a steroid?

No, Tilistigmin 15mg Tablet is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Tilistigmin 15mg Tablet work by preventing the breakdown of a chemical called acetylcholine.

Does it cause weight gain?

No, Tilistigmin 15mg Tablet does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.

Is Tilistigmin 15mg Tablet safe to use?

Yes, Tilistigmin 15mg Tablet is safe if used in the dose and duration prescribed by the doctor.

I felt better when I started taking Tilistigmin 15mg Tablet but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Tilistigmin 15mg Tablet. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.

Can I take Tilistigmin 15mg Tablet for constipation?

No, Tilistigmin 15mg Tablet should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.

What should I do if I accidentally take more than the dose required?

You should seek immediate medical help in case of overdose of Tilistigmin 15mg Tablet.Excess of Tilistigmin 15mg Tablet may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.

Does Tilistigmin 15mg Tablet have any abuse potential?

No, there is no evidence of Tilistigmin 15mg Tablet having any abuse potential.

Who should not take Tilistigmin 15mg Tablet?

Tilistigmin 15mg Tablet should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Tilistigmin 15mg Tablet is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 969.
Neostigmine bromide. Chippenham, Wiltshire: Alliance Pharmaceuticals; 1995 [revised 15 Jan. 2015]. [Accessed 28 Jan. 2019] (online) Available from:
Neostigmine. Swinton, Manchester: Pharmaserve Limited; 2015]. [Accessed 25 Mar. 2019] (online) Available from:
Drugs.com. Neostigmine Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Neostigmine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:

Marketer details

Name: Tablets India Limited

Address: Tablets (India) Limited, “Jhaver Centre”, 72 Marshalls Road, Chennai 600 008.

Country of origin: India

MRP

₹49.8

Inclusive of all taxes

10.0 tablets in 1 strip

SOLD OUT

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