Tretiva 20 Capsule

I've had horrible acne since at least 4 years and decided to get help from a dermatologist 1 year ago. Initially I was prescribed Peroduo gel (Adapalene 0.1%) to be applied before bed and cleargel(clindamycin phosphate) during the day. It didn't seem to do anything at all. I was then put on Tretiva - 20 mg (Isotretinoin) oral and the peroduo gel was changed to peroclin(Clindamycin and benzoyl peroxide) gel which worked a little but not much. The cleargel was changed to Clincure - N (Clindamycin and niacinamide). After this failed, I was told to continue with the dosage of isotretinoin brought up to 30mg per day. This also did not do much. After some research on my own, I decided to try stronger medications by myself. I currently take Tretiva 30 daily and use Azelaic Acid 20% cream during the day and Tazarotene 0.1% (Tazret Forte) before bed and although this has helped a lot compared to what the condition of my face was in the past, the problem still persists. I've also tried topical tretinoin 0.05%(Retino - A) but that didn't make a huge difference. I find the tazarotene works better than the tretinoin cream. At the moment, my pimples have gone down in number but I do have a lot of hyperpigmentation on the sides of my face and redness on my cheeks which is sometimes irritated when touched. I use SPF 40 sunscreen when I go outside and as a moisturizer I use Aquasoft FC by Ajanta pharmaceuticals. I'm also prescribed two facewashes - AHAglow S (Morning) by Torrent and Brevoxyl 4% (Evening) What should I do to fix this problem completely? Should I revisit my dermatologist and ask for a dosage increase in the isotretinoin? Any advice or help is highly appreciated. Thank you very much.

I have been suffering from oral lesions inside my mouth since last year . I have visited a number of doctors, dentists, Skin specialists and even a oncologist. However i have not been cured . Initially there was a black small lesion about the size of a small pea which has spread all over my mouth and has blackened the inner skin lining of my mouth . the lesions are not painful however i am alarmed at the way the have spread and now they have reached the outer lining of my lips over where i have started to feel my skin has eroded. Various mouth gels to counter the lesion have been given, like tablets like topicd 40, neasta , menabol, oncotrex 2.5, Tretiva 10, betadine gargle, Tacrox gel, a Penicillin injection and some anti biotics. Yet I have not been cured kindly help me.