Trinexovas 40 Tablet is a combination of medicines used to treat hypertension (high blood pressure) when a single medication is not effective. It helps to lower high blood pressure thus reduces chances of future heart attack and stroke.

Trinexovas 40 Tablet should be taken with food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.

The most common side effects of this medicine include ankle swelling, headache, dizziness, vertigo, tiredness, and taste change. Consult your doctor If any of these bother you, or get worse, or won't go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, level of electrolytes, and blood sugar level checked regularly to make sure that this medicine is working properly.

Uses of Trinexovas Tablet

Hypertension (high blood pressure)

Benefits of Trinexovas Tablet

In Hypertension (high blood pressure)

Trinexovas 40 Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Trinexovas Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trinexovas

Ankle swelling
Headache
Dizziness
Tiredness
Palpitations
Sleepiness
Increased blood uric acid
Glucose intolerance
Taste change
Flushing (sense of warmth in the face, ears, neck and trunk)
Upset stomach
Altered blood lipid level
Vertigo

How to use Trinexovas Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trinexovas 40 Tablet is to be taken with food.

How Trinexovas Tablet works

Trinexovas 40 Tablet is a combination of three medicines: Olmesartan Medoxomil, Cilnidipine and Chlorthalidone. Olmesartan Medoxomil is an angiotensin receptor blocker (ARB) and Cilnidipine is a calcium channel blocker (CCB). They work by widening and relaxing the blood vessels, thereby lowering blood pressure. Chlorthalidone is a diuretic which removes extra water and certain electrolytes from the body through urine. Over time it also works by relaxing blood vessels and improving blood flow.

Safety advice

Alcohol

UNSAFE

Trinexovas 40 Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Trinexovas 40 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Trinexovas 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Trinexovas 40 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Trinexovas 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Trinexovas 40 Tablet may be needed. Please consult your doctor.
Use of Trinexovas 40 Tablet is not recommended in these patients.

Liver

CAUTION

Trinexovas 40 Tablet should be used with caution in patients with liver disease. Dose adjustment of Trinexovas 40 Tablet may be needed. Please consult your doctor.
Use of Trinexovas 40 Tablet is not recommended in patients with severe liver disease.

What if you forget to take Trinexovas Tablet?

If you miss a dose of Trinexovas 40 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Trinexovas 40 Tablet

₹24.8/Tablet

Olmin Trio 40 Tablet

Eris Lifesciences Ltd

₹27.29/tablet

10% costlier

Olvan Trio 40 Tablet

Sun Pharmaceutical Industries Ltd

₹10.4/tablet

58% cheaper

Olkem Trio 40 Tablet

Alkem Laboratories Ltd

₹25.5/tablet

3% costlier

Omen Trio 40/12.5 Tablet

Medley Pharmaceuticals

₹18.5/tablet

25% cheaper

Olmitel-Trio 40mg/10mg/12.5mg Tablet

El-Dorado Bio-Tech Pvt Ltd

₹15/tablet

40% cheaper

View all substitutes

Quick tips

You have been prescribed Trinexovas 40 Tablet for the treatment of high blood pressure.
Lowering high blood pressure helps prevent strokes and heart attacks.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Trinexovas 40 Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
Use of Trinexovas 40 Tablet during pregnancy or breastfeeding is unsafe.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Patient concerns

I am a patient of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinal condition of high blood pressure. Please see a physician.

Some times I had lot of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.

I'm type 2 diabetic patient with hypertension, l am taking following medicines Tezloc 40 - OD Glimisave Max-1 forte. BBF Glimisave Max-2 forte Cd Rozavel -5. Hs My usual blood pressure -80/145 Usual Blood glucose levels :fasting -120 PP-180 Hba1c - 7.6 Pl suggest me whether I need any change in medicines etc. I'm taking Januvia-100 also

Dr. Nabajit Talukdar

Interventional Cardiology

seems ok basically need control of blood pressure and hypertension get an ecg n echo done

High blood sugar lavel. Gallstone. High blood pressure

Dr. Sanjay Bhatt

Physician

Need to proper investigate and examine. So plz consult doctor nearby.or you can consult me at snergy multiple speciality clinic RD CITY ,BALJEET COMPLEX NEAR SRS MARKET SECTOR 52 gurgaon 9XXXXXX .Advice to maintain calories intake as per weight ,regular walk or aerobic exercises ,on time take your medicines and once a month visit your diabetologist for routine examination and investigations. Will definitely controlled your sugar and u can live healthy life.

User feedback

Patients taking Trinexovas 40 Tablet

Once A Day

98%

Twice A Day

What are you using Trinexovas Tablet for?

High blood pr*

75%

Heart attack

25%

*High blood pressure

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Olmesartan medoxomil. Parsippany, New Jersey: Daiichi Sankyo, Inc.; 2009. [Accessed 11 Apr. 2019] (online) Available from:
PubChem. Cilnidipine. [Accessed 11 Apr. 2019] (online) Available from:
Cilnidipine and Chlorthalidone [Prescribing Information]. Worli, Mumbai: J. B. CHEMICALS & PHARMACEUTICALS LTD.; 2021. [Accessed 14 Aug. 2024] (online) Available from:

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd

Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.