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Xapilis 5 Tablet
Prescription Required
Product introduction
Xapilis 5 Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart. It is used to reduce the risk of stroke and heart attack.
Xapilis 5 Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone elective knee or hip replacement surgeries. It can be taken with or without food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases.
Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
The most common side effect of Xapilis 5 Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include hematoma, anemia, and nausea.
Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding, or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
Uses of Xapilis Tablet
- Treatment and prevention of Blood clots
Benefits of Xapilis Tablet
In Treatment and prevention of Blood clots
Formation of blood clots blocks one or more veins, usually in your legs. Xapilis 5 Tablet is used to prevent formation of blood clots near the surface of your skin. It dissolves the clots and also relieves pain and inflammation by increasing the blood flow. This improves the overall healing process. Take it as prescribed by the doctor. The condition usually improves on its own in some time. Additionally, the doctor might recommend applying heat to the painful area, elevating the affected leg, using an over-the-counter painkiller and possibly wearing compression stockings.
Side effects of Xapilis Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xapilis
- Hemorrhage
- Hematoma
- Anemia (low number of red blood cells)
- Bruise
- Nausea
How to use Xapilis Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xapilis 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Xapilis Tablet works
Xapilis 5 Tablet is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Xapilis 5 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Xapilis 5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Xapilis 5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Xapilis 5 Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Xapilis 5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Xapilis 5 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Xapilis 5 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Xapilis 5 Tablet may be needed. Please consult your doctor.
However, Xapilis 5 Tablet dose adjustment may not be needed in patients with the mild liver disease.
However, Xapilis 5 Tablet dose adjustment may not be needed in patients with the mild liver disease.
What if you forget to take Xapilis Tablet?
If you miss a dose of Xapilis 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Xapilis 5 Tablet can be taken with or without food. Night time administration is not preferable.
- It interacts less with food or other medicines. Hence, frequent dose changes are not required.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
- Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Xapilis 5 Tablet temporarily.
- Notify your doctor if you have any kidney problem.
- Do not stop taking medication without talking to your doctor.
Fact Box
Chemical Class
Phenylpiperidines
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Oral Factor Xa Inhibitors
FAQs
Can I cut the tablet of Xapilis 5 Tablet?
If you have difficulty swallowing the whole tablet, the tablet may be crushed and mixed with water, or 5% dextrose in water, or apple juice or apple puree. Remember to crush the medicine just before you take it.
What if I miss a dose of Xapilis 5 Tablet?
If a dose is missed, the patient should take Xapilis 5 Tablet immediately and then continue with twice daily intake as before.
What are the side effects of taking Xapilis 5 Tablet?
Xapilis 5 Tablet may cause bleeding in eyes, stomach, nose, etc and anemia which may cause tiredness or paleness. It may also lower your blood pressure which may make you faint or have a quickened heartbeat and nausea. Blood tests may show an increase in gamma glutamyltransferase (GGT), which may be due to liver problems.
What is Xapilis 5 Tablet used for?
Xapilis 5 Tablet is used to reduce the risk of stroke and blood clots in people who have atrial fibrillation. In atrial fibrillation, the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes. Xapilis 5 Tablet also helps to reduce the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery and treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again.
How dangerous is Xapilis 5 Tablet?
While using Xapilis 5 Tablet you should be aware of the risks involved such as it can cause excessive bleeding being a blood thinner. Hence, do not stop taking the medication without speaking to your doctor. If you have epidural or spinal anesthesia or a spinal puncture while taking Xapilis 5 Tablet then you may be at risk of developing a blood clot in or around your spine which can result in paralysis in some patients. Hence, inform the doctor beforehand if you have had any such procedure.
Do I need to stop Xapilis 5 Tablet before surgery?
Consult your doctor who will tell you whether you have to stop it or not. It will depend on the type of procedure involved. For instance, if there is moderate to high risk of bleeding during the procedure you will have to stop taking Xapilis 5 Tablet 48 hours before surgery.
Is Xapilis 5 Tablet a blood thinner?
Yes, Xapilis 5 Tablet belongs to a class of medicines known as anticoagulant or blood thinner. It prevents your blood from clotting by preventing formation of an important component of blood clotting (factor Xa).
What are the symptoms of overdosage of Xapilis 5 Tablet?
Xapilis 5 Tablet, when taken more than the recommended dose, may cause unusual bleeding or bruising, red, brown, or pink urine, red or black, tarry stools and coughing up or vomiting blood or material that looks like coffee grounds. Consult your doctor immediately or seek emergency medical attention in a nearby hospital.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 79-80
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 366-67.
- Apixaban. Princeton, New Jersey: Bristol-Myers Squibb Company; 2012. [Accessed 24 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Apixaban. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Apixaban. [Accessed 14 Mar. 2019] (online) Available from:
- Apixaban [Prescribing Information]. Verna, Goa, Indoco Remedies Ltd.; 2021. [Accessed 09 Jun, 2023] (online) Available from:
- Northwestern Memorial Hospital. patient Education: Apixaban. [Accessed 09 Jun, 2023] (online) Available from:
- Drugs.com. Apixaban Pregnancy and Breastfeeding Warnings. [Accessed 14 Mar. 2019] (online) Available from:
Marketer details
Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Country of origin: India
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