Author Details
Written By
MMST, MBBS
Reviewed By
M.Pharm, MBBS
Last updated
26 Nov 2023 | 12:00 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Zhquine 400mg Tablet


Product introduction

Zhquine 400mg Tablet is used to treat autoimmune conditions such as rheumatoid arthritis and systemic lupus erythematosus. It slows the disease's progression and relieves pain, swelling, and redness. It is also used in patients with type 2 diabetes mellitus to improve glycemic control.

Zhquine 400mg Tablet is used to treat joint diseases leading to severe painful swelling and redness of the joints that can lead to difficulty in movement.

Uses of Zhquine Tablet

Benefits of Zhquine Tablet

In Treatment of Rheumatoid arthritis

Rheumatoid arthritis is an autoimmune condition where your body’s immune system (which usually fights bacteria and viruses) attacks your body’s own cells. Zhquine 400mg Tablet stops that from happening and can relieve the symptoms of this condition such as pain, swelling, and stiffness in your joints. It can also slow down joint damage, reduce disability, and enable you to be as active for as long as possible. It can take several weeks or months to notice the effect of the medicine. You should continue taking it until your doctor says it is okay to stop using the medicine.

In Treatment of Systemic lupus erythematosus (SLE)

Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. Zhquine 400mg Tablet prevents the release of substances in the body that cause inflammation. It can be used to treat a great many different inflammatory and allergic conditions. It lowers your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching and other allergic-type reactions.

You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.

In Treatment of Type 2 diabetes mellitus

In addition to diet and exercise, Zhquine 400mg Tablet helps improve glycemic control and reduces glycated hemoglobin (HbA1c) levels in patients with type 2 diabetes mellitus.

Side effects of Zhquine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zhquine

  • Blurred vision
  • Headache
  • Diarrhea
  • Abdominal pain
  • Vomiting
  • Nausea
  • Decreased appetite
  • Skin rash
  • Itching
  • Affect lability

How to use Zhquine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zhquine 400mg Tablet is to be taken with food.

How Zhquine Tablet works

Zhquine 400mg Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system that causes inflammation (swelling) and pain in the joints. This slows the progression of the underlying disease. It has also been suggested that hydroxychloroquine may increase insulin sensitivity and improve beta-cell function, thereby improving glycemic control in patients with type 2 diabetes mellitus.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Zhquine 400mg Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Zhquine 400mg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Zhquine 400mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Zhquine 400mg Tablet may cause side effects which could affect your ability to drive.
You may get eye problems while taking this medicine. This may affect your ability to drive.
Kidney
CAUTION
Zhquine 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zhquine 400mg Tablet may be needed. Please consult your doctor.
This medicine can affect your eyes. Regular eye check up is recommended while you are taking this medicine.
Liver
CAUTION
Zhquine 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zhquine 400mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zhquine 400mg Tablet
₹11.2/Tablet
HCQS 400 Tablet
Ipca Laboratories Ltd
₹15.46/tablet
38% costlier
HYQ 400 Tablet
Ipca Laboratories Ltd
₹15.46/tablet
38% costlier
Oxcq 400 Tablet
Wallace Pharmaceuticals Pvt Ltd
₹13.79/tablet
23% costlier
ZY-Q 400 Tablet
Zydus Cadila
₹13.79/tablet
23% costlier
Hydroquin 400mg Tablet
Sun Pharmaceutical Industries Ltd
₹5/tablet
55% cheaper

Quick tips

  • You have been prescribed Zhquine 400mg Tablet for the treatment of autoimmune conditions such as rheumatoid arthritis or systemic lupus erythematosus.
  • Take it with food to avoid an upset stomach.
  • It can take 8-12 weeks for Zhquine 400mg Tablet to work. Keep taking it as prescribed.
  • Do not take medicines that neutralise stomach acids (antacids) four hours before and after taking Zhquine 400mg Tablet as they can stop the medicine from being absorbed properly from your gut.
  • Have regular eye tests done while taking this medicine. Stop taking it and inform your doctor immediately if you notice any changes in your vision.
  • It can cause lowering of blood glucose level. Inform your doctor if you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.

Fact Box

Chemical Class
4-Aminoquinoline Derivative
Habit Forming
No
Action Class
Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics

Patient concerns

arrow
Diabetes mellitus type 2 ,thirst
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
Suffering from type 2 diabetes rheumatoid arthritis , asthma which medicine should I use
Dr. Jagruti Shah
Diabetology
Most of the diabetic drugs can be given in Rheumatoid arthritis and asthma patients however however steroids treatments is given many times in asthma and Rhumatoid arthritis should be given with very caution in diabetic patients if indicatedMost suitable some times are insulin injections
arrow

FAQs

How to take the Zhquine 400mg Tablet?

Zhquine 400mg Tablet comes as a tablet to be taken by mouth. It should be taken with food or a glass of milk to prevent an upset stomach and nausea. Take it as per dose and duration suggested by the doctor and finish the complete course. Zhquine 400mg Tablet should be used regularly as advised by your doctor. Do not stop taking it without talking to your doctor first. If you have also taking antacids, then take Zhquine 400mg Tablet at least 4hours before or after these products.

How long does it take for Zhquine 400mg Tablet to start working?

HCQS takes some time to show its effects. It may even take a few weeks or months before you see an improvement in your symptoms of rheumatoid arthritis or other autoimmune diseases. However, it is important that you be patient and keep taking this medication regularly. Your doctor may prescribe some additional medications in the interim for temporary relief from the symptoms.

Does Zhquine 400mg Tablet have any effect on vision?

Yes, though uncommon, HCQS can affect vision especially if taken at higher doses or for a period of time (> 5 years). The symptoms include reading or seeing difficulties (words, letters, or parts of objects missing), sensitivity to light, blurred distant vision, and seeing light flashes or streaks. If you notice any of these symptoms, consult your doctor immediately. Your doctor may carry out various eye tests and then decide if Zhquine 400mg Tablet needs to be discontinued. You may also be advised to get certain eye tests done periodically if you have been prescribed HCQS.

Do I need to get any tests done during Zhquine 400mg Tablet treatment?

An eye test is required before your treatment with HCQS starts and should be repeated every 12 months. Also, your doctor may advise you to get your blood counts (CBC) and liver function test (LFT) checked regularly. Your doctor may discontinue HCQS if any abnormality is detected.

Is Zhquine 400mg Tablet an opioid, a painkiller, a steroid, or an anti-inflammatory medicine? How does it work?

Zhquine 400mg Tablet is an antimalarial medicine with anti-inflammatory and immunomodulatory properties. It is neither a steroid nor an opioid nor a painkiller. In malaria, Zhquine 400mg Tablet destroys the harmful parasite which causes the illness. Whereas in rheumatoid arthritis, it reduces inflammation of the joints and provides relief.

Do I need to be careful with Zhquine 400mg Tablet if I am a diabetic?

Yes, you need to be careful while using HCQS if you have diabetes. HCQS can lower your blood glucose levels to dangerous levels so much so that you may even lose consciousness(severe hypoglycemia). Keep a regular check on your blood glucose levels and if it starts to fall, contact your doctor immediately. Your doctor may alter the doses of your anti-diabetic medications as per your blood glucose levels.

I am on antacids since a long time, which is necessary for me. Can I still take Zhquine 400mg Tablet?

Yes, you can take HCQS, provided you keep a gap of at least 4 hours between HCQS and antacid. If this gap is not maintained, then the antacid may interfere with the absorption or working of HCQS. As a result, you may not experience the full benefits of HCQS.

Can I take ibuprofen while taking Zhquine 400mg Tablet?

Yes, you may take ibuprofen and HCQS together. They do not have any significant interactions and do not interfere with the working of each other.

What can I expect if I stop taking Zhquine 400mg Tablet?

If you stop taking HCQS without consulting your doctor, your illness may get worse. Therefore, do not stop taking HCQS without consulting your doctor, even if you start feeling better.

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 630.
  2. Vinetz JM, Clain J, Bounkeua V, Eastman RT, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1402-405.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 669-71.
  4. Hydroxychloroquine sulfate. Girona, Spain: Sanofi-aventis SA; 2017. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Hydroxychloroquine. Bridgewater, New Jersey: sanofi-aventis U.S; 2006. [Accessed 02 Apr. 2019] (online) Available from:External Link
  6. Hydroxychloroquine sulfate. St. Michael, Barbados: Concordia Pharmaceuticals Inc.; 2017. [Accessed 17 Jun. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004;80(5): 4-6. [Accessed 02 Apr. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link
  9. Indian Council of Medical Research. Clinical Guidance and Management of Adult COVID-19 Patients. [Accessed 03 Jul. 2023]. (online) Available from:External Link
  10. Hydroxychloroquine sulfate [Prescribing Information]. Ahmedabad, Gujarat: Amneal Pharmaceuticals Pvt. Ltd.; 2023. [Accessed 03 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Ambience Pharma
Address: 1, Ganga Vihar, Opp Avdoot Mandal Ashram, Jawalapur, Haridwar, Uttarakhand - 249407, India
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

MRP
112
Inclusive of all taxes
10.0 tablets in 1 strip
SOLD OUT
Notify me
Available options
Available options
Same salt composition:Hydroxychloroquine (400mg)
https://onemg.gumlet.io/epf1dtoymcv3sbkzuspl.png
Same salt composition
https://onemg.gumlet.io/qkdhgo7ram1mle08cya9.png
Verified by doctors
https://onemg.gumlet.io/ehvn8wef9oaoewteak8d.png
Popularly bought
https://onemg.gumlet.io/xnv1s7snefeql2hkalfr.png
Trusted quality
Why buy these from 1mg?question-mark

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.