Test Detail
Understanding the Test
Interpreting Results
FAQ's
City Price Info
Home Collection
Other Tests
Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
Want to know more?
Read our Editorial Policy

C-Peptide, Fasting

8001050 23% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. Overnight fasting ( 8-12 hrs). Do not eat or drink anything except water before the test.

Understanding C-Peptide, Fasting


What is C-Peptide, Fasting?

C-Peptide test measures the amount of C-Peptide in the blood or urine. It is a chemical produced by the pancrease in almost the same proportion as insulin. Hence, it can be used as an indicator of the amount of insulin produced in the body. This test is mainly used to distinguish between Type I and Type II diabetes. Type I diabetes is characterized by negligible amounts of insulin and C-peptide. However, in type II diabetes, insulin and C-Peptide levels are beyond normal.

This test is also recommended by doctors to check the treatment of diabetes.

Reduced calorie intake and weight management can aid in managing C-peptide levels.

What is C-Peptide, Fasting used for?

The C-peptide test should be performed:

·     To help evaluate insulin production by the beta cells in the pancreas

·     To help determine the cause of low blood sugar (hypoglycemia) whether it is due to insulin-producing tumors in the body or due to insulin injections (medicinal insulin)

·     To monitor how well the insulinomas (tumors) are responding to the treatment: Decreasing levels of C-peptide in someone with an insulinoma indicate a response to treatment; levels that are increasing may indicate a tumor recurrence

·     To distinguish between type I and type II diabetes mellitus

·     To help evaluate a person diagnosed with metabolic syndrome (set of abdominal obesity, increased blood glucose and/or insulin resistance, abnormal blood lipid levels, and high blood pressure)

·     After pancreatic transplantation: In case of pancreatic islet cell transplants, intended to restore the ability to make insulin, C-peptide levels may be used to verify the effectiveness of treatment and continued success of the procedure.



Interpreting C-Peptide, Fasting results


Interpretations

High levels:

·   A high level of C-peptide generally indicates a high level of endogenous insulin production which may be in response to high blood glucose levels caused by glucose intake or insulin resistance.

·   High levels of C-peptide are also seen with insulinomas.

·   High levels of C-peptide may be seen with low blood potassium, Cushing syndrome, and renal failure.

Low levels: 

- A low level of C-peptide indicates a low level of insulin production by the beta cells that can be seen in diabetes or when production is suppressed by treatment with exogenous insulin.


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about C-Peptide, Fasting


Frequently Asked Questions about C-Peptide, Fasting

Q. Where does C-peptide come from?

C-peptide comes from pancreas. It is released into the blood as a by-product of insulin production. Beta cells produce proinsulin which is a biologically inactive molecule. This molecule splits apart to form one molecule of C-peptide and one molecule of insulin.

Q. Does C-peptide level help in diagnosing diabetes?

C-peptide level may help in differentiating type 1 diabetes from type 2 diabetes, but does not actually help in the diagnosis of diabetes. However, it can help your physician in the treatment of diabetes. In case of type 2 diabetes, a fall in C-peptide levels and insulin levels may indicate that the oral hypoglycemic tablets may not help the patient and insulin injection therapy should be started. Thus, C-peptide level can guide the treatment of diabetes.

Q. Can drugs increase C-peptide level?

Yes, the sulphonylurea class of drug, which is used in the treatment of type 2 diabetes, can lead to an increase in C-peptide level. However, this happens if the beta cell reserve of the pancreas is enough. Examples of sulphonylurea drugs include Chlorpropamide, Glimepiride, Glipizide, Glyburide, and Tolbutamide.

Q. How does C-peptide test help in the treatment of type 2 diabetes?

In type 2 diabetes, there can be insulin resistance. To cope up with this resistance, the body produces and releases more insulin, which can also lead to beta cell damage. Type 2 diabetics usually are treated with oral drugs to stimulate the pancreas to make more insulin or decrease insulin resistance (cells to be more sensitive to the insulin that is already being made). Gradually, there can be beta cell damage to such an extent that type 2 diabetics may make very little insulin and require insulin injections. Any insulin that the body makes will be reflected in the C-peptide level. Therefore, the C-peptide test can be used to monitor beta cell activity and capability over time and to help a doctor determine when to begin insulin treatment.

Q. What is stimulated C-peptide test?

If the test is to diagnose either type 1 or type 2 diabetes, an injection of glucagon may be given into the arm between two blood samples in an attempt to stimulate insulin production. Patients with type 1 diabetes mellitus have low C-peptide levels on glucagon stimulation.

Q. Is there any risk associated with this test?

There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.
+ more

C-Peptide, Fasting test price for other cities


Price inAhmedabadRs. 800
Price inAllahabadRs. 800
Price inBangaloreRs. 800
Price inBhopalRs. 800
Price inChandigarhRs. 800
+ more

Book a C-Peptide, Fasting test at home near me

Easy online booking
Search for tests and packages, book a time and select address for seamless at-home lab tests.
Live tracking of phlebotomist
Stay informed with live tracking of our phlebotomist's location for seamless sample collection.
Safe collection
Our phlebotomists follow strict safety protocols to collect samples at home on time.
Sample received at lab
Your sample is bought to our laboratory for testing by our qualified experts.
Quick reports, free follow up
Reports are sent to your email. A free doctor follow up is provided to understand the report better
Test conducted by
Tata 1mg Labs (Tata 1mg Technologies Private Limited )
ISO certified
Know more

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.