Coagulation Profile (PT/INR & aPTT)
Understanding Coagulation Profile (PT/INR & aPTT)
What is Coagulation Profile (PT/INR & aPTT)?
Coagulation profile helps to determine the concentration of coagulation factors in the blood. It helps to assess the blood's ability to dissolve a clot as well as its clotting time. It is useful for evaluating the risk of excessive bleeding or developing clots (thrombosis).This profile includes two tests, Activated Partial Thromboplastin Time test and Prothrombin Time test.
This profile is recommended for the diagnosis of bleeding or clotting disorders, before a surgery, to patients undergoing the treatment for these diseases.
It is also suggested as a screening test before conceiving to mitigate the risk of birth defects in a baby.
What is Coagulation Profile (PT/INR & aPTT) used for?
Coagulation Profile is done:
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In case of excessive unexplained bleeding
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In case of easy bruising
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In acute conditions such as Disseminated intravascular coagulation
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In chronic conditions such as liver disease
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To monitor the patients taking medicines affecting clotting ability
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Before surgery
What does Coagulation Profile (PT/INR & aPTT) measure?
Contains 2 tests
PT INR (Prothrombin Time)
A PT INR (Prothrombin Time) test helps to detect bleeding or clotting disorders. This test measures the time a blood sample takes to clot after chemicals are added to it. INR is a calculation that adjusts the chemicals added to the sample to measure PT and make the test results comparable among different labs.
Know more about PT INR (Prothrombin Time)
Activated Partial Thromboplastin Time
Interpreting Coagulation Profile (PT/INR & aPTT) results
Interpretations
Prothrombin time: 11 s - 15 s
Activated partial thromboplastin time: 25 s - 35 s
Reference range may vary from lab to lab*
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Results of PT |
Results of PTT |
Can be seen in the following conditions |
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Prolonged |
Normal |
Diseases of liver, Vitamin K deficiency, Defective factor VII, Chronic disseminated intravascular coagulation |
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Normal |
Prolonged |
Hemophilia A or B, Factor XI deficiency, Von Willebrand disease, Factor XII deficiency, Presence of lupus anticoagulant |
|
Prolonged |
Prolonged |
Defective factor I, II, V or X, Severe liver disease, Acute disseminated intravascular coagulation |
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Coagulation Profile (PT/INR & aPTT)
Frequently Asked Questions about Coagulation Profile (PT/INR & aPTT)
Q. How is the blood sample taken?
Q. In what conditions can shortened PTT be seen?
Q. What other tests can be advised by the doctor in case of abnormal coagulation profile?
Q. Is there any risk associated with the withdrawal of blood sample procedure?
Q. What conditions can cause coagulation disorders?
Other tests
