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Understanding the Test
Test Measures
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References
Other Tests
Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Comprehensive Gold Full Body Checkup with Smart Report in Gurgaon

Comprehensive Gold Full Body Checkup with Smart Report in Gurgaon Includes 82 testsView All
You need to provide
Blood, Urine
This test is for
Male, Female
Test Preparation
  1. Overnight fasting (8-12 hrs) is required. Do not eat or drink anything except water before the test.
  2. The urine sample must preferably be the first morning midstream urine (part of urine that comes after the first and before the last stream). Collect the urine sample in a sealed and sterile screw-capped container provided by our sample collection professional. Ensure that the urethral area (from where the urine is passed) is clean & container doesn't come in contact with your skin. Women are advised not to give the sample during the menstrual period unless prescribed. You should submit all the required samples for this package at once during the scheduled sample collection.

Understanding Comprehensive Gold Full Body Checkup with Smart Report in Gurgaon


What is Comprehensive Gold Full Body Checkup with Smart Report in Gurgaon?

Comprehensive Gold Full Body Checkup with Smart Report includes a wide range of tests available at an affordable price in Gurgaon with Tata 1mg labs. This routine checkup is tailored to assess your overall health and identify any potential health problems or diseases at an early stage. This early detection enables your doctor to provide recommendations for lifestyle modifications or medications to manage your condition and formulate an overall treatment plan. 

Comprehensive Gold Full Body Checkup with Smart Report includes a total of 78 tests that check your liver, heart, and kidney functions; blood sugar; thyroid status; lipid profile; blood counts; vitamins; urine; and more. In addition to all the features of the Comprehensive Silver Full Body Checkup Package, it also provides testing for C-reactive protein, rheumatoid factor, hepatitis B antigen, and a more-detailed urine examination. This package is a part of our ‘premium range’ of diagnostic tests and can be ordered once every 6 to 12 months or as recommended by your doctor.

What does Comprehensive Gold Full Body Checkup with Smart Report measure?

Contains 82 tests

A Comprehensive Gold Full Body Checkup with Smart Report allows for the detection, monitoring, and management of acute and chronic health issues or diseases even before the initial symptoms show up. Getting a checkup done regularly allows one to keep a check on their health and is one of the most important parts of preventive healthcare. With a Comprehensive Gold Full Body Checkup with Smart Report, doctors can track organs functioning and abnormalities related to them, which can help take proper measures at the right time to avoid health issues.

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Serum Calcium

A Serum Calcium test measures the levels of calcium in the body. Calcium is the most abundant mineral in the body, and the majority of it is present in the bones and teeth, and the remaining portion (around 1%) is found in the blood. It is normally present in two forms in blood in about equal amounts, namely "bound calcium", which is attached to proteins in the blood, and "free calcium or ionized calcium", which is not attached to any protein. 

A Serum Calcium test cannot be used to check for a lack of calcium in your diet or osteoporosis (loss of calcium from bones) as the body can have normal calcium levels even in case of dietary deficiency of calcium. Moreover, the body can normalize mild calcium deficiency by releasing the calcium stored in bones.

Know more about Serum Calcium

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Serum Iron Studies Basic

A Serum Iron Studies Basic test measures the level of iron in the body. It comprises a series of blood tests, including serum iron test that helps to evaluate iron level, total iron binding capacity (TIBC) test that helps to assess the ability of the body to transport iron in the blood, unsaturated iron binding capacity (UIBC) test that reflects binding of iron with transferrin which is the main protein that binds with iron, and transferrin saturation test that checks how many places on your transferrin that can hold iron are actually doing so.

Know more about Serum Iron Studies Basic

  • Total Iron Binding Capacity

  • Iron Serum

  • Unsaturated Iron Binding Capacity

  • Transferrin Saturation

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Vitamin Profile

A Vitamin Profile covers testing of three vitamins, including vitamins B9, B12, and D. These vitamins are required by your body to reduce health risks, build immunity, and maintain your overall health. Deranged levels of these vitamins can give rise to lethargy, irritation, muscle spasm, fatigue, anemia, psychological disorders, or toxicity if not given timely attention. 

Know more about Vitamin Profile

  • Vitamin B12

  • A Vitamin B12 test measures your vitamin B12 levels. Vitamin B12 is essential for various health aspects, such as maintaining a healthy nervous system, making red blood cells, and creating the genetic material of our cells. Low vitamin B12 levels are more likely to occur in older adults, children, vegans, vegetarians, people with diabetes, individuals who underwent gastric bypass surgery, women who are breastfeeding, and in conditions that impact absorption of this vitamin, like Crohn’s disease. Higher vitamin B12 levels are uncommon as excessive vitamin B12 is usually removed through the urine. However, some conditions, such as liver diseases and myeloproliferative disorders, can cause an increase in vitamin B12 levels, thereby affecting blood cell production.

  • Vitamin D (25-Hydroxy)

  • A Vitamin D (25-Hydroxy) test measures the levels of vitamin D in the body. It is an essential nutrient that can be synthesized in the body upon healthy exposure to sunlight or absorbed from dietary sources. It majorly exists in two forms: Vitamin D2 (ergocalciferol) and Vitamin D3 (cholecalciferol). Vitamin D2 is present in plants, such as yeast or mushrooms, and is available as a supplement in fortified foods, and vitamin D3 is found in foods like cheese, green vegetables, mushrooms, egg yolks, and fatty fish.

    Both forms of vitamin D (D2 and D3) need to undergo some chemical changes before being available for use in the body. These chemical changes take place in the liver or kidneys. The liver converts vitamin D to 25-hydroxyvitamin D (25-OH vitamin D). A Vitamin D (25-Hydroxy) test measures the level of this 25-OH vitamin D as it is the primary form of vitamin D that circulates in the blood.

Microalbumin Creatinine Ratio, Urine

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Diabetes Screening (HbA1C & Fasting Sugar)

A Diabetes Screening (HbA1C & Fasting Sugar) test includes a glycosylated hemoglobin test and a glucose-fasting blood test. The glycosylated hemoglobin test measures the percentage of glycosylated hemoglobin in the blood, while a glucose-fasting blood test measures the glucose level during fasting. Glucose is the main form of sugar utilized by the body to release energy; it is absorbed by the intestine and distributed to all organs through blood. These tests help your doctor to monitor your blood sugar levels and manage your diabetes well. 

Know more about Diabetes Screening (HbA1C & Fasting Sugar)

  • HbA1c (Hemoglobin A1c)

  • An HbA1c (Hemoglobin A1c) test precisely measures the percentage of sugar-coated or glycated hemoglobin in your blood. The test results represent the proportion of hemoglobin in your blood that has been glycated. 

    Hemoglobin, a vital protein found in red blood cells, is responsible for transporting oxygen throughout the body. Hemoglobin A is the most abundant form of hemoglobin, and when blood sugar levels increase, a higher proportion of hemoglobin A becomes glycated. As red blood cells have a lifespan of approximately 120 days, the sugar molecules remain attached to the hemoglobin for the duration of the cell's life. Consequently, the HbA1c test offers insight into your average blood sugar levels over the past 8 to 12 weeks. 

  • FBS (Fasting Blood Sugar)

  • A fasting blood sugar test measures the level of glucose in the body under overnight fasting conditions. Glucose serves as the energy currency of the body and is broken down through metabolism to produce energy. This process is controlled by hormones and enzymes in organs such as the liver and pancreas. The hormone insulin, produced by the pancreas, is responsible for regulating blood glucose levels. When these levels are high, such as after a meal, insulin is secreted to transport glucose into cells for energy production. Elevated glucose levels in the body after fasting may indicate a risk of developing prediabetes or diabetes, which can be of two types- Type 1, caused by little or no insulin production, and Type 2, caused by insulin resistance or decreased insulin production.

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CBC (Complete Blood Count)

A CBC (Complete Blood Count) test evaluates red blood cells (RBCs), white blood cells (WBCs}, and platelets. Each of these blood cells performs essential functions–RBCs carry oxygen from your lungs to the various body parts, WBCs help fight infections and other diseases, and platelets help your blood to clot–so determining their levels can provide significant health information. A CBC test also determines the hemoglobin level, a protein in RBC that carries oxygen from the lungs to the rest of your body. Evaluating all these components together can provide important information about your overall health.

Know more about CBC (Complete Blood Count)

  • Absolute Lymphocyte Count

  • Absolute Neutrophil Count

  • Differential leukocyte Count

  • There are five types of WBCs: neutrophils, lymphocytes, monocytes, eosinophils, and basophils. A Differential leukocyte Count test measures the percentage of each type of WBC in the blood. Leukocytes or WBCs are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

    This further contains

    • Differential Neutrophil Count
    • Differential Lymphocyte Count
    • Differential Monocyte Count
    • Differential Eosinophil Count
    • Differential Basophil Count
  • Red Blood Cell Count

  • Hb (Hemoglobin)

  • A Hb (Hemoglobin) test measures the concentration of hemoglobin protein in your blood. Hemoglobin is made up of iron and globulin proteins. It is an essential part of RBCs and is critical for oxygen transfer from the lungs to all body tissues. Most blood cells, including RBCs, are produced regularly in your bone marrow. The Hb test is a fundamental part of a complete blood count (CBC) and is used to monitor blood health, diagnose various blood disorders, and assess your response to treatments if needed.

  • Platelet Count

  • Absolute Basophil Count

  • An Absolute Basophil Count test measures the total number of basophils in the blood. Basophils are small, spherically-shaped cells that originate from bone marrow and make up almost 1% of the total white blood cells in the body. They attack a foreign substance and release proteins like histamine and heparin to destroy harmful substances, such as allergens, pathogens, or parasites. Histamine helps widen the blood vessels and make space for more immune cells to come to the site of infection or injury, whereas heparin acts as a blood-thinning agent and helps to avoid blood clotting at that site.

  • Absolute Monocyte Count

  • An Absolute Monocyte Count test measures the total number of monocytes in the blood. Monocytes are a type of WBC that originate from bone marrow and travel to different tissues via the blood. Once they are inside the tissue, these cells get converted to macrophages (a type of cell that digest harmful substances). Monocytes are the second line of defense mechanism of the human body after neutrophils. These cells are also responsible for the removal of injured or dead cells, microorganisms, and other insoluble particles from the blood. 

  • Absolute Eosinophil Count

  • Hematocrit

  • A Hematocrit test measures the proportion of red blood cells (RBCs) in your blood as a percentage of the total blood volume. It is a crucial part of a complete blood count (CBC) and helps in assessing your blood health. RBCs are responsible for carrying oxygen from the lungs to different parts of the body. The hematocrit test provides valuable information about your blood's oxygen-carrying capacity.

    Higher-than-normal amounts of RBCs produced by the bone marrow can cause the hematocrit to increase, leading to increased blood density and slow blood flow. On the other hand, lower-than-normal hematocrit can be caused by low production of RBCs, reduced lifespan of RBCs in circulation, or excessive bleeding, leading to a reduced amount of oxygen being transported by RBCs. Monitoring your hematocrit levels is essential for diagnosing and managing various blood-related disorders.

  • Mean Corpuscular Volume

  • A Mean Corpuscular Volume test measures the average size of your red blood cells, which carry oxygen through your body. This test tells whether your RBCs are uniform or vary significantly in size.

  • Mean Corpuscular Hemoglobin

  • An MCH test measures the average amount of hemoglobin in a single red blood cell (RBC). Hemoglobin is an iron-containing protein in RBCs, and its major function is to transport oxygen from the lungs to all body parts. This test provides information about how much oxygen is being delivered to the body by a certain number of RBCs.

  • Mean Corpuscular Hemoglobin Concentration

  • An MCHC test measures the average amount of hemoglobin in a given volume of RBCs. MCHC is calculated by dividing the amount of hemoglobin by hematocrit (volume of blood made up of RBCs) and then multiplying it by 100. 

  • Mean Platelet Volume

  • An MPV test measures the average size of the platelets in your blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days. 

    Platelets help stop bleeding whenever there is an injury or trauma to a tissue or blood vessel by adhering and accumulating at the injury site, and by releasing chemical compounds that stimulate the gathering of more platelets. After these steps, a loose platelet plug is formed at the site of injury, and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or are not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding. 

  • PDW

  • RDW CV

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CRP (C-Reactive Protein) - Quantitative

A CRP test measures the levels of CRP protein in your body. This test helps detect the presence of inflammation in the body. It is a non-specific test as it cannot diagnose a condition by itself or determine its exact location or cause. 

CRP is an acute phase reactant protein that is produced by the liver in response to an inflammation in the body. This inflammation may be due to tissue injury, infection, autoimmune diseases, or cancer. CRP levels are often increased before the onset of other symptoms of inflammation such as pain, redness, fever, or swelling. These levels fall as the inflammation subsides.

Know more about CRP (C-Reactive Protein) - Quantitative

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HBsAg Screening - Rapid

An HBsAg Screening - Rapid test confirms the presence of hepatitis B virus (HBV) in a suspected individual. HBsAg is the first serological marker, within 1 to 10 weeks, to appear in the blood after recent exposure to HBV. Persistence of this marker for more than 6 months implies chronic (long-term) HBV infection which may lead to liver damage (scarring or cirrhosis). A person who has a chronic infection is capable of spreading the infection to healthy individuals, even if they do not show or experience any symptoms.

Know more about HBsAg Screening - Rapid

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Lipid Profile

A Lipid Profile test assesses the level of specific fat molecules called lipids in the blood and helps determine the risk of heart ailments. This test determines the amount of different types of lipids, including total cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides. Lipids play a pivotal role in the functioning of the body. They are crucial components of the cell membranes and hormones, provide cushioning, and are a storehouse of energy. Any alterations in the lipid levels may lead to potential heart ailments, making their monitoring crucial.

Know more about Lipid Profile

  • Cholesterol - LDL

  • A Cholesterol - LDL test measures the concentration of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol plays an important role in your body. It carries cholesterol from your liver to other parts of the body where it's needed for things like building cell walls and making hormones. However, it is often referred to as "bad" cholesterol because when present in excess in your blood, it can stick to your blood vessel walls leading to the formation of plaque, making them narrow and less flexible. When this happens, it's harder for the blood to flow, which can lead to heart problems, like heart attacks and strokes. By measuring LDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and can recommend appropriate preventive or treatment strategies.

  • Triglycerides

  • A Triglycerides test measures the amount of triglycerides in the blood and helps evaluate your risk of developing cardiovascular diseases. Triglycerides are a type of fat (lipid) that your body uses as a source of energy. When you consume more calories than your body needs, the excess calories are converted into triglycerides and stored in fat cells for later use. High triglyceride levels can contribute to the hardening and narrowing of arteries, increasing the risk of heart attack, stroke, and other related conditions. 

  • Cholesterol - Total

  • A Cholesterol - Total test measures the total amount of cholesterol (fats) in your blood. Cholesterol is mainly synthesized in the liver and partially in the intestines. It acts as a building block for cell membranes, serves as a precursor to vital hormones, and helps in the production of bile acids that help digest fats. Cholesterol is transported through the blood by two kinds of proteins: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). An optimal amount of these proteins is necessary for proper body functioning.

  • Cholesterol - HDL

  • A Cholesterol - HDL test measures the concentration of high-density lipoprotein (HDL) cholesterol in the blood. HDL cholesterol plays a crucial role in maintaining cardiovascular health, as it helps transport excess low-density lipoprotein (LDL) cholesterol from the bloodstream back to the liver for excretion. This process prevents the buildup of plaque on the blood vessel walls, which can cause them to become narrow and less flexible. Higher levels of HDL cholesterol are generally associated with a lower risk of heart problems, such as heart attacks and strokes. By measuring HDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and can recommend appropriate preventive or treatment strategies, including lifestyle modifications and medications.

  • Very Low Density Lipoprotein

  • A Very Low Density Lipoprotein test measures the concentration of very-low-density lipoprotein (VLDL) cholesterol in the blood. VLDL cholesterol plays a vital role in the body's metabolic processes. It is produced by the liver and is used to transport triglycerides, a type of fat, from the liver to various tissues throughout the body, where they are either utilized for energy or stored for later use. Though VLDL cholesterol is essential for the body's normal functioning, it is harmful if present in excess amounts. By measuring VLDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and recommend appropriate preventive or treatment strategies.

  • Total Cholesterol/HDL Cholesterol Ratio

  • LDL/HDL Ratio

  • An LDL/HDL Ratio test measures the ratio of low-density lipoproteins (LDL) to high-density lipoproteins (HDL) in your blood. These two types of lipoproteins carry cholesterol throughout the body. LDL, often referred to as the 'bad' cholesterol, carries cholesterol to the cells that need it. However, if there is too much LDL cholesterol in the blood, it can combine with other substances and form plaque in the arteries, leading to cardiovascular diseases. On the other hand, HDL, often referred to as the 'good' cholesterol, helps remove other forms of cholesterol, including LDL, from the bloodstream. It transports cholesterol back to the liver, where it is broken down and eliminated from the body, thus reducing the risk of cholesterol buildup and heart disease. The LDL/HDL ratio is a significant indicator of cardiovascular health. A high ratio indicates a higher amount of 'bad' cholesterol relative to 'good' cholesterol, implying a higher risk of developing heart disease. Conversely, a lower ratio implies a higher amount of 'good' cholesterol relative to 'bad' cholesterol, indicating a lower risk.

  • Non HDL Cholesterol

  • A Non HDL Cholesterol test looks for the “bad” cholesterol particles that are likely to contribute to heart problems. These bad particles include LDL (low-density lipoprotein) cholesterol, VLDL (very-low-density lipoprotein) cholesterol, and remnants of other cholesterol-carrying molecules. Cholesterol is a waxy substance that circulates in your bloodstream and is essential for various bodily functions. However, too much of “bad” types of cholesterol can build up in your arteries and increase the risk of heart conditions. LDL and VLDL cholesterol particles are often referred to as the "bad" cholesterol because they can stick to the walls of your arteries and form plaque, narrowing the arteries and restricting blood flow to your heart. By measuring non-HDL cholesterol, your doctor can assess your risk of heart disease and determine if any interventions or lifestyle changes are needed to protect your heart.

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Rheumatoid Factor - Quantitative

A Rheumatoid Factor - Quantitative test detects and measures rheumatoid factor (RF), a specific type of autoantibody (protein produced by the immune system in response to a foreign substance), in your blood. We all have antibodies which are also known as immunoglobulins in the blood. These antibodies are protective proteins that help to fight infection. However, autoantibodies may attack your own tissues mistakenly identifying them as “foreign substances”.   

An RF test is sensitive but not very specific as rheumatoid factor can also be found in the body in diseases other than RA and Sjögren’s syndrome. This autoantibody is also produced in the body during some persistent bacterial and viral infections.

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Peripheral Smear Examination

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Urine R/M (Urine Routine & Microscopy)

A Urine R/M (Urine Routine & Microscopy) test involves gross, chemical, and microscopic evaluation of the urine sample.

  1. Gross examination: It involves the visual examination of the urine sample for color and appearance. Normally, the urine color ranges from colorless or pale yellow to deep amber, depending on the urine’s concentration. Things such as medications, supplements, and some foods such as beetroot can affect the color of your urine. However, unusual urine color can also be a sign of disease.

    In appearance, the urine sample may be clear or cloudy. A clear appearance is indicative of healthy urine. However, the presence of red blood cells, white blood cells, bacteria, etc. may result in cloudy urine, indicating conditions such as dehydration, UTIs, kidney stones, etc. Some other factors such as sperm and skin cells may also result in a cloudy appearance but are harmless.

  2. Chemical examination: It examines the chemical nature of the urine sample using special test strips called dipsticks. These test strips are dipped into the urine sample and they change color when they come in contact with specific substances. The degree of color change gives an estimate of the amount of the substance present. Some of the common things detected include protein, urine pH, ketones, glucose, specific gravity, blood, nitrites, and urobilinogen among others.

  3. Microscopic examination: It involves the examination of the urine sample under the microscope for casts, crystals, cells, bacteria, and yeast. 

Know more about Urine R/M (Urine Routine & Microscopy)

  • Urobilinogen

  • Ketone

  • Nitrite

  • Colour

  • Appearance

  • Specific Gravity

  • Pus Cell

  • Epithelial Cell

  • Casts

  • Crystals

  • Protein Urine

  • Ph for Urine

  • Urine Glucose

  • Yeast

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LFT (Liver Function Test)

An LFT (Liver Function Test) helps determine the health of your liver by measuring various components like enzymes, proteins, and bilirubin. These components help detect inflammation, infection, diseases, etc., of the liver and monitor the damage due to liver-related issues.

Know more about LFT (Liver Function Test)

  • Bilirubin Indirect

  • A Bilirubin Indirect test measures the amount of indirect or unconjugated bilirubin in your body. Bilirubin is a yellowish byproduct primarily produced when your body breaks down aged red blood cells (RBCs). When RBCs finish their lifespan of 120 days, they break down and pass to your liver. Indirect bilirubin, a form of bilirubin that is unconjugated (not soluble in water), is bound to the protein albumin that helps transport it to the liver. When the liver processes the bilirubin, it unbinds from the albumin and binds to a sugar molecule, making it water-soluble. This water-soluble bilirubin is mixed with bile, excreted in the bile ducts, and stored in your gallbladder. Finally, bile is released into the small intestine to help digest fat and is eventually excreted with your stool as a waste product.

  • Bilirubin Direct

  • A Bilirubin Direct test measures the amount of direct or conjugated bilirubin present in your body. Bilirubin is a yellowish byproduct primarily produced when the body breaks down aged RBCs. When the RBCs finish their lifespan of 120 days, they break down and pass to the liver. In the liver, direct bilirubin–a form of bilirubin conjugated with glucuronic acid (sugar)–is processed, mixed with bile, and then excreted in the bile ducts and stored in your gallbladder. Finally, the bile is released into the small intestine where it is further broken down and helps digest fat. It is eventually excreted within your stool as a waste product.

    Elevated levels of bilirubin can be indicative of various liver or bile duct issues. Additionally, higher bilirubin levels might result from an increased breakdown of red blood cells in the body.

  • Gamma Glutamyl Transferase

  • Gamma-Glutamyl Transferase (GGT) is an enzyme found in various organs, with the highest concentration in the liver. Usually, this enzyme is present in low levels in the blood. However, when there is liver damage or disease, GGT is released into the bloodstream, causing an increase in GGT levels. In addition to the liver, GGT can also be elevated in conditions affecting the bile ducts or the pancreas. It is usually, the first liver enzyme to rise in the blood when there is any damage or obstruction in the bile duct, making it one of the most sensitive liver enzyme tests for detecting bile duct problems.

  • Bilirubin Total

  • A Bilirubin Total examination quantifies the levels of total bilirubin in the body, encompassing both indirect (unconjugated) and direct (conjugated) bilirubin. Bilirubin, a yellowish waste substance, is primarily generated during the breakdown of aging red blood cells (RBCs) in the body. After their typical lifespan of 120 days, RBCs disintegrate in the liver, leading to the production of a substantial amount of bilirubin. It is crucial for this bilirubin to be eliminated from the body.

  • SGPT

  • An SGPT test measures the amount of ALT or SGPT enzyme in your blood. ALT is most abundantly found in the liver, but it is also present in smaller amounts in other organs like the kidneys, heart, and muscles. Its primary function is to convert food into energy. It also speeds up chemical reactions in the body. These chemical reactions include the production of bile and substances that help your blood clot, break down food and toxins, and fight off an infection.

    Elevated levels of ALT in the blood may indicate liver damage or injury. When the liver cells are damaged, they release ALT into the bloodstream, causing an increase in ALT levels. Therefore, the SGPT/ALT test is primarily used to assess the health of the liver and to detect liver-related problems such as hepatitis, fatty liver disease, cirrhosis, or other liver disorders.

  • Alkaline Phosphatase (ALP)

  • An Alkaline Phosphatase (ALP) test measures the quantity of ALP enzyme present throughout the body. The main sources of this enzyme are the liver and bones. It exists in different forms depending on where it originates, such as liver ALP, bone ALP, and intestinal ALP. In the liver, it is found on the edges of the cells that join together to form bile ducts. 

    ALP levels can be increased during pregnancy as it is found in the placenta of pregnant women. It is also higher in children because their bones are in the growth phase. ALP is often high during growth spurts (a short period when an individual experiences quick physical growth in height and body weight).

  • SGOT

  • An SGOT test measures the levels of serum glutamic-oxaloacetic transaminase (SGOT), also known as aspartate aminotransferase (AST), an enzyme produced by the liver. SGOT is present in most body cells, most abundantly in the liver and heart. The primary function of this enzyme is to convert food into glycogen (a form of glucose), which is stored in the cells, primarily the liver. The body uses this glycogen to generate energy for various body functions.

  • Protein Total, Serum

  • A Protein Total, Serum test measures the amount of proteins in the body. Proteins are known as the building blocks of all cells and tissues. They play a crucial role in the growth and development of most of your organs and in making enzymes and hormones. There are two types of proteins found in the body, namely albumin and globulin. About 60% of the total protein is made up of albumin, which is produced by the liver. It helps to carry small molecules such as hormones, minerals, and medicines throughout the body. It also serves as a source of amino acids for tissue metabolism. On the other hand, globulin is a group of proteins that are made by the liver and the immune system. They play an important role in liver functioning, blood clotting, and fighting off infections.

    This further contains

    • Serum Albumin
    • Protein Total
    • Globulin, Serum
    • Albumin/Globulin Ratio, Serum
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Thyroid Profile Total (T3, T4 & TSH)

A Thyroid Profile Total (T3, T4 & TSH) measures the levels of three hormones in the blood, namely triiodothyronine hormone (T3) total, thyroxine hormone (T4) total, and thyroid-stimulating hormone (TSH). T3 and T4 are thyroid hormones that help regulate metabolism and energy levels in the body. On the other hand, TSH is produced by the pituitary gland and stimulates the thyroid gland to produce T3 and T4 hormones. The serum levels of the thyroid hormones and TSH have an inverse relationship, i.e., low T4 (as observed in hypothyroidism) and high T4 (as seen in hyperthyroidism) levels are associated with high and low TSH levels, respectively.

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  • Thyroxine - Total

  • A Thyroxine - Total measures both the bound and unbound/free form of thyroxine (T4) hormone in the blood. T4 exists in the blood in two forms: bound (attached to proteins) and free (not attached to proteins). Most of the T4 circulating in the blood is bound to proteins and only a small part is free. It is necessary to maintain a fine balance of these forms to ensure the proper functioning of the body.

  • Triiodothyronine Total

  • A Triiodothyronine Total measures triiodothyronine, also known as T3, hormone that is produced by the thyroid gland. T3 hormone plays an important role in regulating the body's metabolism, energy levels, and growth & development. It exists in the blood in two forms: free T3 and bound T3. Free T3 is not bound to proteins in the blood and is the active form of T3. Whereas, bound T3 is bound to proteins, such as albumin and thyroid hormone binding globulin (THBG), which prevent it from entering the body tissues.

Urinary Creatinine

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KFT with Electrolytes (Kidney Function Test with Electrolytes)

A KFT with Electrolytes (Kidney Function Test with Electrolytes) determines the health of your kidneys. It evaluates various parameters such as creatinine, urea, and uric acid along with electrolytes (sodium, potassium, and chlorine). This test also helps diagnose possible kidney disorders, such as inflammation, infection, or functional damage in the kidneys.

Know more about KFT with Electrolytes (Kidney Function Test with Electrolytes)

  • Potassium

  • A Potassium test measures the levels of potassium in your body. Potassium is one of the key electrolytes that helps in the functioning of the kidneys, heart, nerves, and muscles. It also balances the effect of sodium and helps keep your blood pressure normal. The body absorbs the required amount of potassium from the dietary sources and eliminates the remaining quantity through urine. Potassium level is normally maintained by the hormone aldosterone. Aldosterone acts on the nephrons present in the kidneys and activates the sodium-potassium pump that helps the body reabsorb sodium and excrete potassium. This aids in maintaining a normal and steady potassium level in the blood. 

  • Uric Acid

  • Chloride

  • A Chloride test measures the amount of chloride in your body. Chloride is present in all body fluids and is found in the highest concentration in the blood and extracellular fluid (fluid present outside the cells). The body gets most of the chloride through dietary salt (sodium chloride or NaCl) and a small amount through other food items. The required amount of chloride is absorbed in the body and the excess amount is excreted by the kidneys through urine. When the chloride is combined with sodium it is mostly found in nature as salt. Chloride generally increases or decreases in direct relationship to sodium but may also change without any changes in sodium levels when there are problems with the body's pH. Usually, the normal blood chloride level remains steady with a slight fall after meals (because the stomach produces hydrochloric acid using chloride from the blood after we eat food).

  • Sodium

  • A Sodium test is used to measure the amount of sodium in your body. Sodium is present in all body fluids and is found in the highest concentration in the extracellular fluid. The body absorbs the required amount of sodium through dietary salts and the remaining is eliminated through the kidneys. The body keeps your blood sodium within a normal and steady range by following three mechanisms:

    • By producing hormones that control the elimination of sodium through urine, such as natriuretic peptides and aldosterone.

    • By producing hormones that prevent water loss, such as antidiuretic hormone (ADH) or vasopressin.

    • By controlling thirst (an increase in blood sodium level can make you thirsty and cause you to drink water, returning your sodium to normal).

    These mechanisms regulate the amount of water and sodium in the body and control blood pressure by keeping the amount of water in check. When the level of sodium in the blood changes, the water content in your body changes. These changes can be associated with dehydration, edema, and change in blood pressure.

  • Blood Urea

  • A Blood Urea test measures the level of urea in the blood. Urea is a byproduct of protein metabolism. Proteins you consume in your diet are digested and converted into amino acids, which are then utilized by the body. This metabolic process produces a toxic byproduct known as ammonia. Ammonia is then rapidly converted into urea by your liver. Urea is comparatively less toxic than ammonia and is transported to the kidneys via the blood. The kidneys then filter it out through the urine. This process continues and the body keeps producing and eliminating urea, maintaining its low and steady levels in the blood.

  • BUN/Creatinine Ratio

  • Blood Urea Nitrogen

  • A Blood Urea Nitrogen test measures the levels of urea nitrogen in the blood. Blood urea is a waste product that is formed in the liver when you eat food and the protein is metabolized into amino acids. This process leads to the production of ammonia that is further converted into urea. Both ammonia and urea are nitrogenous compounds. Your liver releases urea into the blood which is then carried out to the kidneys. In the kidneys, urea is filtered from the blood and flushed out of the body via urine. This is a continuous process, so a small amount of urea nitrogen always remains in the blood.

    In the case of a kidney or liver disease, there is a change in the amount of urea present in the blood. If your liver produces urea in an increased amount or if there is any problem in kidney functioning, there might be difficulty in filtering out the waste products from the blood, which can result in increased urea levels in the blood.

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References

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  2. Drawz S, Linden M. Complete Blood Count (CBC) Basics [Internet]. Washington, DC: AACC; 10 May 2016 [Accessed 02 Aug. 2023]. Available from: https://www.aacc.org/science-and-research/clinical-chemistry-trainee-council/trainee-council-in-english/pearls-of-laboratory-medicine/2016/complete-blood-count-basicsExternal Link
  3. Paramastri R, Hsu CY, Lee HA, Lin LY, Kurniawan AL, Chao JC. Association between Dietary Pattern, Lifestyle, Anthropometric Status, and Anemia-Related Biomarkers among Adults: A Population-Based Study from 2001 to 2015. Int J Environ Res Public Health. 2021 Mar 26;18:3438. [Accessed 02 Aug. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/33810272/External Link
  4. Anemia in Chronic Kidney Disease [Internet]. USA: National Institute of Diabetes and Digestive and Kidney Diseases; Sept. 2020 [Accessed 02 Aug. 2023]. Available from: https://www.niddk.nih.gov/health-information/kidney-disease/anemiaExternal Link
  5. Know your Kidney Numbers: Two Simple Tests. NY: National Kidney Foundation; 30 Jan. 2017 [Accessed 02 Aug. 2023]. Available from: https://www.kidney.org/atoz/content/know-your-kidney-numbers-two-simple-tests#:~:text=CKD%20is%20evaluated%20using%20twoExternal Link
  6. Kidney Testing: Everything You Need to Know. Centers for Disease Control and Prevention; 24 Mar. 2022 [Accessed 02 Aug. 2023]. Available from: https://www.cdc.gov/kidneydisease/publications-resources/kidney-tests.htmlExternal Link
  7. Saker B.M. Everyday drug therapies affecting the kidneys. Sydney: NPS MedicineWise; 1 Jan. 2000 [Accessed 02 Aug. 2023]. Available from: https://www.nps.org.au/australian-prescriber/articles/everyday-drug-therapies-affecting-the-kidneysExternal Link
  8. Gounden V, Bhatt H, Jialal I. Renal Function Tests. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing; Jan. 2023 [Accessed 02 Aug. 2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507821/External Link
  9. Lala V, Zubair M, Minter DA. Liver Function Tests. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing; Jan. 2023 [Accessed 02 Aug. 2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482489/External Link
  10. Liver Function Tests [Internet]. Stanford Medicine Health Care; [Accessed 02 Aug. 2023]. Available from: https://stanfordhealthcare.org/medical-tests/b/blood-test/types/liver-function-test.htmlExternal Link
  11. Common Liver Tests [Internet]. Johns Hopkins Medicine; [Accessed 02 Aug. 2023]. Available from: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/common-liver-testsExternal Link
  12. Diabetes [Internet]. WHO; 5 Apr. 2023 [Accessed 02 Aug. 2023]. Available from: https://www.who.int/news-room/fact-sheets/detail/diabetesExternal Link
  13. Your Diabetes Care Schedule [Internet]. USA: CDC; 19 Apr. 2023 [Accessed 02 Aug. 2023]. Available from: https://www.cdc.gov/diabetes/managing/care-schedule.htmlExternal Link
  14. Vitamin D [Internet]. NIH; 12 Aug. 2022 [Accessed 02 Aug. 2023]. Available from: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/External Link
  15. Aparna P, Muthathal S, Nongkynrih B, Gupta SK. Vitamin D deficiency in India. J Family Med Prim Care. 2018 Mar-Apr;7(2):324-330. [Accessed 02 Aug. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060930/External Link
  16. Vitamin B12 [Prescribing Information]. FDA; Jan. 2021 [Accessed 02 Aug. 2023]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/080737Orig1s040lbl.pdfExternal Link
  17. Vitamin B12 or folate deficiency anemia. NHS; 20 Feb. 2023 [Accessed 02 Aug. 2023]. Available from: https://www.nhs.uk/conditions/vitamin-b12-or-folate-deficiency-anaemia/External Link

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