Test Detail
Understanding the Test
Test Measures
Interpreting Results
FAQ's
References
Other Tests
Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Globulin, Serum

You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. Overnight fasting (8-12 hrs) is required. Do not eat or drink anything except water before the test.

Understanding Globulin, Serum


What is Globulin, Serum?

A ​Globulin, Serum test is used to measure the amount of globulin protein in your body. This test is used to detect various health problems, including liver diseases, kidney diseases, acute infections, inflammatory diseases, and immunity-related diseases. It is often performed as part of routine health checkups. 

Proteins are responsible for forming the structural part of most of the body's organs and also help in making enzymes and hormones. Globulin protein is needed by the body for growth and development. 

Your doctor may suggest a Globulin, Serum test if you experience symptoms such as fatigue, abnormal urination, unexplained swelling in legs and feet, yellowing of the skin and eyes, and allergy. This test may also be used to check the response of an undergoing treatment related to the liver and kidneys and to determine your nutritional status. Usually, overnight fasting (8-12 hours) is preferred before a globulin test; eat or drink anything except water before the test.

Test result ranges are approximate and may differ slightly between different labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The test results will help them determine your medical condition, make recommendations for lifestyle modifications such as diet and exercise, decide whether or not medication will be required to manage your overall health, and formulate your treatment plan.

What is Globulin, Serum used for?

A Globulin, Serum test is done: 

  • As part of routine health checkups.

  • If you have symptoms suggestive of liver disease.  

  • If you have symptoms suggestive of kidney disease.

  • If you have symptoms of allergy. 

  • To monitor the treatment response and progression of an existing liver and kidney disease.

  • To determine the nutritional status.

What does Globulin, Serum measure?

A Globulin, Serum test measures the levels of globulin protein in the blood. Globulin is one of the major proteins (about 40% of the total protein) found in the body and is produced by the liver and immune cells. It usually exists in different forms: alpha globulins, beta globulins, and gamma globulins. These forms play an important role in liver and kidney functioning, blood clotting, and fighting off infections. 

Interpreting Globulin, Serum results


Interpretations

The normal range for serum globulin content is 2.0-3.5 g/dl.


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Globulin, Serum


Frequently Asked Questions about Globulin, Serum

Q. What does a Globulin, Serum test indicate?

A Globulin, Serum test is used to determine your kidney and liver health by measuring the amount of globulin in your body. This test is also used to check if your body is absorbing enough proteins.

Q. Is fasting required before a Globulin, Serum test?

Yes, usually overnight fasting is preferred before a Globulin, Serum test. You may be asked not to eat or drink anything except water before the test.

Q. Is there any risk associated with a globulin test?

There is usually no risk associated with this test. However, some people may feel a slight sting when a needle is pricked and may experience some bleeding that is normal and usually not bothersome. Rarely, some people may also experience slight swelling or bruising at the site of the needle prick. Applying ice 3-4 times a day for about a week may help reduce swelling and bruising. If it does not get better, consult your doctor.

Q. What are the natural sources to increase globulin levels?

You must consult your doctor if your test reports suggest abnormal globulin levels. However, to increase your globulin level naturally, add protein-rich foods, such as soy, seafood, dried fruits, whole grains, and eggs, to your diet.

Q. What does high globulin level indicate?

A high globulin level may be a sign of chronic active hepatitis, alcoholic hepatitis, acute infection, and chronic inflammatory diseases.
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