Vitamin D Profile (D2, D3 & D Total)
Understanding Vitamin D Profile (D2, D3 & D Total)
What is Vitamin D Profile (D2, D3 & D Total)?
The vitamin -D profile measures the levels of vitamin D in your body. This profile offers a Vitamin D3 test, Vitamin D2 test, and Vitamin D test (Total). You may need this test if you have symptoms such as bone pain, muscle weakness, fatigue, loss of appetite, nausea, and frequent urination. This test is also a useful indicator of osteoporosis (bone weakness), rickets (bone malformation), and osteomalacia(bone softening). Measures such as eating food containing vitamin D and getting more sunlight may help maintain optimal vitamin D levels in your body.
What is Vitamin D Profile (D2, D3 & D Total) used for?
- To determine vitamin D deficiency when calcium level is low or a person has symptoms of vitamin D deficiency such as bone malformation in children (rickets), bone weakness, softness, or fracture in adults (osteomalacia).
- Before starting osteoporosis therapy.
- To monitor that the treatment is correct for patients who are receiving Vitamin D supplements, calcium, phosphorus, and/or magnesium supplements.
- To diagnose/monitor problems with parathyroid gland functioning since the parathyroid hormone (PTH) is essential for vitamin D activation.
- To monitor the health status of individuals with diseases that interfere with fat absorption (e.g., cystic fibrosis and Crohn’s disease) and in patients who have undergone gastric bypass surgery.
What does Vitamin D Profile (D2, D3 & D Total) measure?
Contains 3 testsVitamin D3
Vitamin D Total
Vitamin D2
Interpreting Vitamin D Profile (D2, D3 & D Total) results
Interpretations
Vitamin D level below the normal reference range indicates that vitamin D deficiency. This can be because of less sun exposure, dietary deficiency, or due to decreased absorption from the intestine.
Vitamin D level above the normal reference range indicates vitamin D intoxication. This is usually due to excess supplementation of the vitamin.
Range:
The normal range of vitamin D Total is measured as nanograms per milliliter (ng/mL) or nmol/L and can vary from lab to lab.
|
Level |
Reference range (ng/mL) |
|
Deficiency |
<20 ng/mL |
|
Insufficiency |
20-30 ng/mL |
|
Sufficiency |
30-100 ng/mL |
|
Toxicity |
>100 ng/mL |
Note:
· The assay measures both vitamin D2 (Ergocalciferol) and vitamin D3 (Cholecalciferol) metabolites of vitamin D.
· There can be seasonal variation in 25 (OH) vitamin D level, with values being 40-50% lower in winter than in summer. It is also influenced by sunlight, latitude, skin pigmentation, sunscreen use, and hepatic function.
· 25 (OH) vitamin D levels can vary with age
· 25 (OH) vitamin D level is increased in pregnancy.
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