Thyroglobulin in Chandigarh

Thyroglobulin (Tg) test measures the amount of thyroglobulin, a protein made by the thyroid gland. This protein serves as the source for the production of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). The Tg test is primarily used as a marker for thyroid cancer esp. monitoring treatment and recurrence of thyroid cancer after treatment or surgery. In healthy people, the thyroid gland releases very low levels of Tg into the bloodstream along with T3 and T4. Tg levels may also be raised in certain non-cancerous conditions of the thyroid like goiter, increased thyroid activity (eg, Graves disease), or thyroiditis, etc. However, an individual with thyroid cancer may have higher Tg levels than healthy individuals. One also needs to be aware that Tg levels may be falsely high/ low in the presence of anti-Tg autoantibodies (TgAb) and hence prior levels of TgAb should be determined for monitoring Tg in thyroid cancer patients.